Evidence map›Paper›PMID 38707456›Full record

ArticleHeliyon2024

A new anti-inflammatory lupane in

Dure-E Shahwar, N Shehzadi, M Tanveer Khan, S Zia, M Saleem, S Akhtar, Farhat Saghir, S Iftikhar, A Mobashar, S Naheed and 2 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dure-E ShahwarPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
N ShehzadiPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
M Tanveer KhanFaculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan.
S ZiaPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
M SaleemPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
S AkhtarPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
Farhat SaghirFaculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
S IftikharPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
A MobasharFaculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
S NaheedPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
N I BukhariPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.
K HussainPunjab University College of Pharmacy, University of the Punjab, Lahore-54000, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate extracts of the stem bark of Methods: The dry powder was macerated separately in three types of solvents to prepare methanol extract (ME), ethyl acetate extract (EE), and chloroform extract (CE). Following in vitro anti-inflammatory screening, the most active extract was selected to isolate the active compound. Both, the active extract and isolated compound were further tested on rats using the carrageenan-induced inflammation model. The blood and paw tissue were subjected to qPCR, and histopathology, respectively. Key findings: CE showed comparatively higher anti-inflammatory activity (85.0-95.0 %) in all in vitro assays, except the heat-induced membrane stabilization model ( Conclusions: This study reveals that chloroform extract of the stem's bark of

Indexed as

Column chromatographyDownregulation of inflammatory markersHussainateZiziphus jujube,Rhamnaceae, anti-inflammatory activity

Identifiers

PMID38707456
PMCPMC11066634

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.