Evidence map›Paper›PMID 38707440›Full record

ArticleHeliyon2024

CDC73 serves as a tumour-promoting factor in oesophageal cancer.

Jie Song, Wenying Guo, Hua Xu, Tao Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jie SongDepartment of Cardiac surgery, Ningbo medical center Lihuili Hospital of Ningbo University, No.57, Xingning Road, Ningbo city 315041, Zhejiang Province, China.
Wenying GuoDepartment of Digestive, Ningbo medical center Lihuili Hospital of Ningbo University, No.57, Xingning Road, Ningbo city 315041, Zhejiang Province, China.
Hua XuDepartment of Thoracic Surgery, First Affiliated Hospital of Nanchang University, Nanchang city 330006, Jiangxi Province, China.
Tao GaoDepartment of Thoracic Surgery, First Affiliated Hospital of Nanchang University, Nanchang city 330006, Jiangxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of human cell division cycle 73 (CDC73) in human cancers has sparked controversy; however, its significance in oesophageal cancer remains elusive. This study aimed to elucidate CDC73 expression and its biological implications in human oesophageal cancer. Our findings unveiled a notable upregulation of CDC73 in both oesophageal cancer cell lines and tissues. Importantly, elevated CDC73 levels in patients with oesophageal cancer correlated with an unfavourable prognosis. Functional investigations revealed that CDC73 knockdown effectively curtailed the proliferation and growth of oesophageal cancer cells both

Indexed as

CDC73Cell apoptosisCell proliferationOesophageal cancerRRP15

Identifiers

PMID38707440
PMCPMC11066309

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.