Evidence map›Paper›PMID 38707361›Full record

ArticleHeliyon2024

Sex differences in the correlation between white matter hyperintensity and 3-month outcome in acute stroke patients.

Junli Ren, Xia Zhang, Haobo Xie, Xinbo Zhou, Jiahan Xu, Haojie Qiu, Jielin Zhou, Wei Xie, Siqi Chen, Xin Lu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Junli RenDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xia ZhangDepartment of Radiology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Haobo XieThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Xinbo ZhouThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Jiahan XuThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Haojie QiuThe Second School of Medicine, Wenzhou Medical University, Wenzhou, China.
Jielin ZhouThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Wei XieThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Siqi ChenThe Second School of Medicine, Wenzhou Medical University, Wenzhou, China.
Xin LuThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Yichuan FanAlberta Institute, Wenzhou Medical University, Wenzhou, China.
Dehao YangDepartment of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guangyong ChenDepartment of Neurology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The severity of white matter hyperintensities (WMH) has been shown to be an independent predictor of poor stroke outcome, but the effect of sex on this correlation has not been investigated further. Therefore, the purpose of our study was to assess whether there was a sex difference between the severity of WMH and poor stroke outcome. Methods: This retrospective study included 449 patients with acute ischemic stroke (AIS) who received intravenous thrombolysis. WMH severity was graded based on the Fazekas scale. The association between WMH severity and stroke outcome was explored through multivariable regression analyses in men and women. Results: Among women, when dividing WMH severity into tertiles, T3 (Fazekas scale >3) had a 5.334 times higher risk for unfavorable outcomes than T1 (Fazekas scale <2) ( Conclusions: The risk of unfavorable outcomes increased proportionally with the enlargement of the WMH severity in females, suggesting the sex-specific value of the WMH severity in optimizing the risk stratification of stroke.

Indexed as

Intravenous thrombolysisOutcomeSex differenceStrokeWhite matter hyperintensities

Identifiers

PMID38707361
PMCPMC11066628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.