Evidence map›Paper›PMID 38707131›Full record

ArticleCureus2024

Real-World Assessment of Personalized Approach With Voglibose Fixed-Dose Combination in Type 2 Diabetes Mellitus.

Nirmal Parmar, Ajay Kumar Gupta, Kunal Jhaveri, Balachandran A, Gaurav Chhaya, Sandeep Kansara, Rathish Nair, Krishnaprasad R Korukonda

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nirmal ParmarDepartment of Internal Medicine, Prisha Medical Care, Ahmedabad, IND.
Ajay Kumar GuptaDepartment of Internal Medicine, Madhumeha Clinic, New Delhi, IND.
Kunal JhaveriDepartment of Internal Medicine, Vishesh Clinic of Internal Medicine, Ahmedabad, IND.
Balachandran ADepartment of Diabetology, ABC Medical Centre, Erode, IND.
Gaurav ChhayaDepartment of Internal Medicine, Shivam Medi Care Clinic, Ahmedabad, IND.
Sandeep KansaraDepartment of Endocrinology, Dr. Sandeep Kansara's Diabetes, Thyroid, and Hormone Clinic, Udaipur, IND.
Rathish NairDepartment of Medical Strategic Affairs, Torrent Pharmaceuticals Ltd., Ahmedabad, IND.
Krishnaprasad R KorukondaDepartment of Medical Strategic Affairs, Torrent Pharmaceuticals Ltd., Ahmedabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-prandial hyperglycemia (PPHG) remains a complex aspect in the management of type 2 diabetes mellitus (T2DM) in the Indian population due to uncertainty in the optimal utilization of alpha-glucosidase inhibitors (AGIs) either as standalone therapy or in combination, whether initiated initially or as a sequential therapy.

methodsThis was a post-approval, observational, multicentric clinical study conducted at 50 centers according to principles of the International Council for Harmonisation of Technical Requirements of Pharmaceuticals for Human Use Guideline for Good Clinical Practice (ICH-GCP) and Declaration of Helsinki and local ethics approval. Descriptive and analytical statistics were applied for conclusion and categorical variables using SPSS version 29.0.1.0 (171) (Armonk, NY: IBM Corp.).

resultsProtocol analyses of 515 cases revealed baseline demographics as follows: age 57.35±10.04 years, weight 72.86±10.92 kg, and BMI 28.33±6.07 kg/m

conclusionVoglibose fixed-dose combination (FDC) demonstrates significant effectiveness at the initial dosage when started early in the management of T2DM and high PPBG levels. Moreover, it exhibits good tolerability, thereby contributing to higher compliance among Indian patients who consume a high-carbohydrate diet.

Indexed as

fbgfixed-dose combinationhba1cppbgtrivoglitortype 2 diabetes mellitus

Identifiers

PMID38707131
PMCPMC11066517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.