Evidence map›Paper›PMID 38707114›Full record

ReviewCureus2024

Delirium Tremens: A Review of Clinical Studies.

Alan D Kaye, Amanda N Staser, Tiombee S Mccollins, Jackson Zheng, Fouad A Berry, Caroline R Burroughs, Michael Heisler, Aya Mouhaffel, Shahab Ahmadzadeh, Adam M Kaye and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Amanda N StaserDepartment of Medicine, Ross University School of Medicine, Miramar, USA.
Tiombee S MccollinsSchool of Medicine, American University of the Caribbean, Miramar, USA.
Jackson ZhengSchool of Medicine, American University of the Caribbean, Miramar, USA.
Fouad A BerrySchool of Medicine, American University of the Caribbean, Miramar, USA.
Caroline R BurroughsSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Michael HeislerDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Aya MouhaffelDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Adam M KayeDepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences University of the Pacific, Stockton, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Giustino VarrassiDepartment of Pain Medicine, Paolo Procacci Foundation, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delirium tremens (DT) is a severe condition resulting from alcohol withdrawal. This review highlights the challenges in diagnosing and managing DT and emphasizes the importance of early recognition and intervention to prevent complications and ensure optimal patient outcomes. The discussion of the pathophysiology of DT, focusing on the neurochemical imbalances involving the neurotransmitters gamma-aminobutyric acid and glutamate, explains how chronic alcohol dependence leads to these imbalances and contributes to the hyperexcitability seen in DT. The management of DT involves ensuring patient safety and alleviating symptoms, primarily through pharmacological approaches, such as benzodiazepines. Closely monitoring vital signs and electrolyte imbalances is necessary due to autonomic dysregulation associated with DT. The mention of the potential complexity of DT when coexisting with other conditions emphasizes the need for additional research to advance comprehension, identify predictive factors, and enhance its management.

Indexed as

alcohol withdrawal deliriumalcohol withdrawal syndromedelirium tremensdtdts

Identifiers

PMID38707114
PMCPMC11069634

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.