Evidence map›Paper›PMID 38706889›Full record

ReviewFrontiers in nephrology2024

CAR T-cell therapy and the onco-nephrologist.

Marco Aurelio Salvino, Alberto Mussetti, Marta Peña, Annalisa Paviglianiti, Abel Santos Carreira, Daniel Rizky, Anna Sureda

Abstract readReview
In one paragraph

Review in Frontiers in nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marco Aurelio SalvinoPrograma Pos Graduacao Medicina Saude (PPGMS), Universidade Federal da Bahia, Salvador, Brazil.
Alberto MussettiL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.
Marta PeñaL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.
Annalisa PaviglianitiL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.
Abel Santos CarreiraL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.
Daniel RizkyL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.
Anna SuredaL'Hospitalet, Institut Català de Oncologia, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell therapy, specifically the revolutionary chimeric antigen receptor (CAR) T-cell therapy, has transformed the landscape of oncology, making substantial strides in practical treatment approaches. Today, established guidelines for diseases such as lymphomas, myelomas, and leukemias actively advocate the utilization of these once-unconventional therapies. The practical impact of these therapies is underscored by their unparalleled efficacy, reshaping the way we approach and implement treatments in the realm of oncology. However, CAR T-cell therapy, with its performance in anti-tumor aggression through cellular action and inflammatory response, also comes with various adverse events, one of which is kidney injury. Therefore, the management of these side effects is extremely important. The integration of knowledge between oncologists and specialized nephrologists has led to the emergence of a new sub-area of expertise for onco-nephrologists specializing in managing kidney complications from immune effector therapies.

Indexed as

acute kidney injuryCAR T-cellimmune effector cellskidneyonco-nephrology

Identifiers

PMID38706889
PMCPMC11066316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.