Evidence map›Paper›PMID 38706886›Full record

ArticleIn silico pharmacology2024

Comparative analyses of anti-inflammatory effects of Resveratrol, Pterostilbene and Curcumin:

Rashmi Patil, Gaurang Telang, Urmila Aswar, Nishant Vyas

Abstract read
In one paragraph

Article in In silico pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rashmi PatilDepartment of Pharmacology Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), Paud Road, Erandwane, Pune, Maharashtra 411038 India.ORCID 0000-0002-0032-9418
Gaurang TelangLogical Life Science Pvt. Ltd, Vadgaon Khurd, Pune, Maharashtra 411041 India.ORCID 0000-0002-2220-5360
Urmila AswarDepartment of Pharmacology Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), Paud Road, Erandwane, Pune, Maharashtra 411038 India.ORCID 0000-0002-4566-7453
Nishant VyasLogical Life Science Pvt. Ltd, Vadgaon Khurd, Pune, Maharashtra 411041 India.ORCID 0000-0002-4198-112X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is an adaptive response that involves activation, and recruitment of cells of innate and adaptive immune cells for restoring homeostasis. To safeguard the host from the threat of inflammatory agents, microbial invasion, or damage, the immune system activates the transcription factor NF-κB and produces cytokines such as TNF-α, IL- 6, IL-1β, and α. Sirtuin 1 (SIRT1) controls the increased amounts of proinflammatory cytokines, which in turn controls inflammation. Three phytoconstituents resveratrol (RES), pterostilbene (PTE), and curcumin (CUR) which are SIRT1- activators and that have marked anti-inflammatory effects ( Graphical abstract: Schematic representation of in-silico and in-vitro analysis of Resveratrol, Pterostilbene, and Curcumin.

Indexed as

InflammationIn- silico docking,In-vitro THP1Metabolic syndromeSIRT1

Identifiers

PMID38706886
PMCPMC11065812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.