Evidence map›Paper›PMID 38706858›Full record

ArticleiScience2024

Accelerated CD8

Lesley R de Armas, Vinh Dinh, Akshay Iyer, Suresh Pallikkuth, Rajendra Pahwa, Nicola Cotugno, Stefano Rinaldi, Paolo Palma, Paula Vaz, Maria Grazia Lain and 1 more

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lesley R de ArmasDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Vinh DinhDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Akshay IyerDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Suresh PallikkuthDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Rajendra PahwaDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Nicola CotugnoResearch Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Stefano RinaldiDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Paolo PalmaResearch Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paula VazInstituto Nacional de Saúde, Marracuene, Maputo Province, Mozambique.
Maria Grazia LainFundação Ariel Glaser contra o SIDA Pediátrico, Maputo, Mozambique.
Savita PahwaDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

Pediatric Adolescent Virus Elimination (PAVE) Martin Delaney CollaboratoryUM1AI164566 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Ann M Chahroudi, Deborah Persaud · 2021 to 2026
$35.5M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
Immunity and HIV persistence in perinatal HIV infectionR01AI127347 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PAHWA, SAVITA · 2016 to 2020
$3.3M
NIAID NIH HHS P30 AI073961NIAID NIH HHS R01 AI127347NIAID NIH HHS UM1 AI164566
6 · The paper itself

Abstract

In perinatal HIV infection, early antiretroviral therapy (ART) initiation is recommended but questions remain regarding infant immune responses to HIV and its impact on immune development. Using single cell transcriptional and phenotypic analysis we evaluated the T cell compartment at pre-ART initiation of infants with perinatally acquired HIV from Maputo, Mozambique (Towards AIDS Remission Approaches cohort). CD8

Indexed as

ImmunologyVirology

Identifiers

PMID38706858
PMCPMC11068557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.