Evidence map›Paper›PMID 38706777›Full record

ArticleStructural equation modeling : a multidisciplinary journal2024

The impact of omitting confounders in parallel process latent growth curve mediation models: Three sensitivity analysis approaches.

Xiao Liu, Zhiyong Zhang, Kristin Valentino, Lijuan Wang

Abstract read
In one paragraph

Article in Structural equation modeling : a multidisciplinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiao LiuThe University of Texas at Austin.
Zhiyong ZhangUniversity of Notre Dame.
Kristin ValentinoUniversity of Notre Dame.
Lijuan WangUniversity of Notre Dame.

Funding

Pathways Linking Early Adversity and Support to Behavioral and Physical HealthR01HD091235 · NICHD · UNIVERSITY OF NOTRE DAME · PI VALENTINO, KRISTIN · 2018 to 2022
$2.8M
NICHD NIH HHS R01 HD091235
6 · The paper itself

Abstract

Parallel process latent growth curve mediation models (PP-LGCMMs) are frequently used to longitudinally investigate the mediation effects of treatment on the level and change of outcome through the level and change of mediator. An important but often violated assumption in empirical PP-LGCMM analysis is the absence of omitted confounders of the relationships among treatment, mediator, and outcome. In this study, we analytically examined how omitting pretreatment confounders impacts the inference of mediation from the PP-LGCMM. Using the analytical results, we developed three sensitivity analysis approaches for the PP-LGCMM, including the frequentist, Bayesian, and Monte Carlo approaches. The three approaches help investigate different questions regarding the robustness of mediation results from the PP-LGCMM, and handle the uncertainty in the sensitivity parameters differently. Applications of the three sensitivity analyses are illustrated using a real-data example. A user-friendly Shiny web application is developed to conduct the sensitivity analyses.

Indexed as

Bayesian methodslatent growth curve modelsmediation analysissensitivity analysisunmeasured confounding

Identifiers

PMID38706777
PMCPMC11068081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.