THE EFFECT OF SKIN ANTISEPSIS AFTER PRIMARY SKIN CLOSURE ON THE INCIDENCE OF SURGICAL SITE INFECTION AFTER ABDOMINAL SURGERY FOR SEPSIS: A PRELIMINARY REPORT OF A RANDOMISED CONTROLLED TRIAL.

I B Ulasi, E O Aigbovo, A I Michael, O O Ayandipo, A Fowotade, U M Ishiyaka, C Ezeme, N A Olagunju, C K Ikwu

Abstract read

In one paragraph

Article in Annals of Ibadan postgraduate medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

I B UlasiDepartment of Surgery, University College Hospital, Ibadan.

E O AigbovoDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan.

A I MichaelDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, University College Hospital, Ibadan.

O O AyandipoDivision of Oncological Surgery, Department of Surgery, University College Hospital, Ibadan.

A FowotadeDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan.

U M IshiyakaDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan.

C EzemeDepartment of Surgery, University College Hospital, Ibadan.

N A OlagunjuDepartment of Surgery, University College Hospital, Ibadan.

C K IkwuDepartment of Surgery, University College Hospital, Ibadan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The role of skin antisepsis after skin closure in abdominal surgery for sepsis is not well reported. This study assessed the effect of skin antisepsis following primary skin closure on surgical site infection (SSI) after contaminated and dirty abdominal surgery. Methods: This was a randomised controlled trial involving adult patients undergoing laparotomy for sepsis. Patients were randomised into a Control (C) group where the wound edge was cleaned once with 70% isopropyl alcohol before being covered with a dry sterile gauze dressing and a Povidone-iodine (PI) group in whom the wound edge was cleaned once with 70% isopropyl alcohol, then covered with a 10% povidone iodine-soaked gauze dressing. Both groups were compared for the presence of SSI. Statistical significance was set at a p value of < 0.05. Results: Thirty-seven patients (C group = 18; PI group = 19) were recruited. The median age was 36 years (Interquartile range, IQR = 72) with a male-to-female ratio of 2.7:1. The overall incidence of SSI was 48.6% (n = 18), comparable between the C group (n=10, 55.6%) and PI group (n = 8; 42.1%) (p = 0.413). In-hospital mortality rate was 10.8 % (n = 4), equally distributed between the groups (p = 1.000). The length of hospital stay was 8 days (IQR = 15) in the C group and 7 days in the PI group (IQR =9) (p = 0.169). Conclusion: In laparotomy for sepsis, skin antisepsis after primary skin closure had no effect on the incidence of surgical site infection.

Indexed as

Abdominal SurgeryAntisepsisSepsisSkin closure

Identifiers

PMID38706616

PMCPMC11065193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.