ArticleCardiovascular endocrinology & metabolism2024
Myocardial function, mechanics and work by echocardiography in adolescents with severe obesity.
Article in Cardiovascular endocrinology & metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Left Atrial Strain in Pediatric Cardiology: Evidence to Date and Future Directions.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026Review
- Obesity-induced left atrial dysfunction across age groups and cardiovascular conditions: a comprehensive review of diagnostic advances and clinical implications.Annals of translational medicine · 2025Review
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Authors and funding
8 authors.
Funding
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Abstract
Introduction: Obesity and its metabolic complications can impact the heart's structure and function in childhood, although demonstrating this impact has been challenging. New echocardiographic parameters such as left atrial strain (LAε) and left ventricular strain (LVε), as well as myocardial work (MW), could reveal subclinical alterations in cardiac function. Objective: The aim is to evaluate the feasibility of these parameters in adolescents with severe obesity and explore their associations with body fat, metabolic comorbidities, and physical capacity. Methods: This is a cross-sectional study in adolescents with obesity who underwent echocardiography with analysis of LAε, LVε and MW using speckle tracking. Feasibility and association with anthropometry, body fat percentage, comorbidities and cardiopulmonary test were analyzed. Results: Twenty adolescents were recruited, 13 (65%) were males, median age 14.2 (interquartile range: 12.9-14.9) years old. The median Conclusion: Echocardiographic evaluation of LAε, LVε and MW is feasible in adolescents with severe obesity. A higher proportion of body fat and the presence of comorbidities are associated with alterations in these new echocardiographic functional parameters suggesting myocardial impact of higher metabolic compromise.
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