ArticleAging clinical and experimental research2024
Secondary osteoporosis prevention: three-year outcomes from a Fracture Liaison Service in elderly hip fracture patients.
Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Anti-osteoporosis medications in persons with and without Parkinson disease in Finland.Archives of osteoporosis · 2026Article
- Position paper: a coordinated approach to fracture and fall prevention from seven international organizations.European geriatric medicine · 2026Article
- Association of implementation of secondary fracture prevention incentives after hip fracture and risk of subsequent fracture in real-world practice.European geriatric medicine · 2026Article
- Risk stratification improves outcomes in an osteoporosis fracture liaison service.Archives of osteoporosis · 2026Article
- Treatment Patterns in Hospitalized Hip Fracture Patients: An Interrupted Time-Series Analysis Around the New Fee for Secondary Fracture Prevention in Japan.Rheumatology and therapy · 2026Article
- Comparative outcomes of osteoporotic fracture management between tertiary hospitals and fracture liaison services in Malaysia.Scientific reports · 2026Article
- Clinical Outcomes of a Coordinator-Based Fracture Liaison Service for Hip Fractures in Korea.Journal of Korean medical science · 2026Article
- The Critical Role of Follow-Up in Fracture Liaison Services for Geriatric Hip Fracture Patients: A Retrospective Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Effectiveness of an integrated hospital-community care pathway for fragility fractures' secondary prevention: the PROMOTER-II study.Archives of osteoporosis · 2025Article
- The Impact of Fracture Liaison Services on Outcomes in Older Patients: A Systematic Review.Cureus · 2025Review
- Real-life effectiveness of a Fracture Liaison Service in reducing short-term mortality and second fractures after hip fracture: a five-year prospective study.Archives of osteoporosis · 2025Article
- Examining Romosozumab Adherence and Side Effects in Osteoporotic Patients After Surgical Fracture Fixation: A Comparative, Descriptive, and Hypothesis-Generating Study with Non-Fractured Controls.Diseases (Basel, Switzerland) · 2025Article
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8 authors.
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Abstract
backgroundHip fractures are the most serious fragility fractures due to their associated disability, higher hospitalization costs and high mortality rates. Fracture Liaison Service (FLS) programs have enhanced the management of osteoporosis-related fractures and have shown their clinical effectiveness.
aimsTo analyze the effect of the implementation of a FLS model of care over the survival and mortality rates following a hip fracture.
methodsWe conducted a prospective cohort study on patients over 60 years of age who suffered a hip fracture before and after the implementation of the FLS in our center (between January 2016 and December 2019). Patients were followed for three years after the index date. Mortality, complications and refracture rates were compared between the two groups using a Multivariate Cox proportional hazard model.
resultsA total of 1366 patients were included in this study (353 before FLS implementation and 1013 after FLS implementation). Anti-osteoporotic drugs were more frequently prescribed after FLS implementation (79.3% vs 12.5%; p < 0.01) and there was an increase in adherence to treatment (51.7% vs 30.2%; p < 0.01). A total of 413 (40.8%) patients after FLS implementation and 141 (39.9%) individuals before (p = 0.47) died during the three-years follow-up period. A second fracture occurred in 101 (10.0%) patients after FLS implementation and 37 (10.5%) individuals before (p = 0.78). Patients after the implementation of the FLS protocol had a lower all cause one-year mortality [adjusted Hazard Ratio (HR) 0.74 (0.57-0.94)] and a decreased risk of suffering a second osteoporotic fracture [adjusted HR 0.54 (0.39-0.75) in males and adjusted HR 0.46 (0.30-0.71) in females].
conclusionsThe implementation of a FLS protocol was associated with a lower all-cause one-year mortality rate and a higher survivorship in elderly hip fracture patients. However, no three-year mortality rate differences were observed between the two groups. We also found a reduction in the complication and second-fracture rates.
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