ArticleJournal of the American Society for Mass Spectrometry2024
A Portable and Reusable Database Infrastructure for Mass Spectrometry, and Its Associated Toolkit (The DIMSpec Project).
Article in Journal of the American Society for Mass Spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Enhanced Environmental PFAS Characterization Using a Virtual High-Resolution Mass Spectral Library Generated by Transfer Learning-Based Neural Network.Environmental science & technology · 2026Article
- Communicating with Stakeholders to Identify High-Impact Research Directions for Non-Targeted Analysis.Analytical chemistry · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Nontargeted analysis (NTA) is a rapidly growing field of techniques that includes the identification of unknown chemical analytes in complex mixtures such as environmental, biological, and food matrices. The use of reference mass spectral databases is a key component of most NTA workflows, providing a high level of confidence for chemical identification when analytical standards are not available, yet effective interlaboratory sharing of research grade spectra remains challenging. The Database Infrastructure for Mass Spectrometry (DIMSpec) project focused on the creation of an open-source toolkit supporting storage and sharing of high-resolution mass spectra with attached sample and methodological metadata. As a demonstration of its utility, the DIMSpec toolkit was used to create a database of curated mass spectra for per- and polyfluoroalkyl substances (PFAS) generated from various sources. While the underlying toolkit is agnostic to analytical targets, this initial release (along with the database schema, mass spectral data, and database tools) should enable PFAS researchers to use these data for their own studies, including the identification of novel PFAS in the environment.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.