Evidence map›Paper›PMID 38704737›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2024

Co-Occurrence of Apathy and Impulse Control Disorders in Parkinson Disease: Variation across Multiple Measures.

Bonnie M Scott, Robert S Eisinger, Roshan Mara, Amtul-Noor Rana, Sable Thompson, Michael S Okun, Aysegul Gunduz, Dawn Bowers

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In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bonnie M ScottDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Robert S EisingerDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Roshan MaraDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Amtul-Noor RanaDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Sable ThompsonDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
Michael S OkunDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Aysegul GunduzDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Dawn BowersDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Together: Transforming and Translating Discovery to Improve HealthTL1TR001428 · NCATS · UNIVERSITY OF FLORIDA · PI MCCORMACK, WAYNE T. · 2015 to 2023
$3.9M
Local field potentials reveal reward processing and impulse control disorders in Parkinson’s diseaseF30NS111841 · NINDS · UNIVERSITY OF FLORIDA · PI EISINGER, ROBERT STEPHEN · 2019 to 2022
$124k
NCATS NIH HHS KL2 TR001429NCATS NIH HHS TL1 TR001428NCATS NIH HHS UL1 TR001427NIH HHSNIH/NCATS Clinical and Translational Science Awards to the University of Florida UL1TR001427NINDS NIH HHS F30 NS111841NINDS NIH HHS F30NS111841Norman Fixel Institute for Neurological DiseasesUF Parkinson's Foundation Center of ExcellenceUF Pruitt Family Endowed Faculty Fellowship
6 · The paper itself

Abstract

objectiveTo determine if the co-occurrence of apathy and impulse control disorders (ICDs) in Parkinson disease is dependent on instrument selection and assess the concurrent validity of three motivation measures by examining interrelationships between them.

methodNinety-seven cognitively normal individuals with idiopathic Parkinson disease (PD) completed the Questionnaire for Impulsive-Compulsive Disorders in Parkinson Disease-Rating Scale (QUIP-RS) and three apathy measures: the Apathy Scale, Lille Apathy Rating Scale, and Item 4 of the Movement Disorder Society-Unified Parkinson Disease Rating Scale.

resultsFifty (51.5%) participants were classified as apathetic on at least one measure, and only four individuals (4.3%) obtained clinically elevated scores on all three measures. The co-occurrence of apathy and ICD varied across measures.

conclusionsWe observed a co-occurrence of apathy and ICDs in PD patients with each apathy instrument; however, limited concurrent validity exists across measures. This is important for future investigations into shared pathophysiology and the design of future clinical trials aimed at improving the early detection and treatment of these debilitating syndromes.

Indexed as

ApathyDisruptive, Impulse Control, and Conduct DisordersParkinson DiseaseAgedFemaleHumansMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesSurveys and QuestionnairesAnhedoniaAnxietyApathyDepressionFatigueImpulse control disordersParkinson’s disease

Identifiers

PMID38704737
PMCPMC11504688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.