ArticleAlzheimer's research & therapy2024
Clinical validity of the Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB) in Mild Cognitive Impairment and Alzheimer's Disease.
Article in Alzheimer's research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Virtual brain and electroencephalography explain the variance of memory alterations in mild cognitive impairment.Alzheimer's research & therapy · 2026Article
- Alterations in topological and dynamical parameters correlate with disease biomarkers and neuropsychological scores in prodromic stages of dementia.Scientific reports · 2026Article
- The adherence of memory clinics to consensus recommendations for dementia diagnosis: A multicentric study in Italy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Cross-Modal Alignment and Rectified Flow-Based Latent Representation Synthesis for Enhanced Speech-Driven Alzheimer's Disease Detection.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- The remote administration of the uniform data set neuropsychological test battery (I-UDSNB) Italian version: normative data.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations.Frontiers in neuroscience · 2025Article
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35 authors.
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Abstract
backgroundThe identification and staging of Alzheimer's Disease (AD) represent a challenge, especially in the prodromal stage of Mild Cognitive Impairment (MCI), when cognitive changes can be subtle. Worldwide efforts were dedicated to select and harmonize available neuropsychological instruments. In Italy, the Italian Network of Neuroscience and Neuro-Rehabilitation has promoted the adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB), collecting normative data from 433 healthy controls (HC). Here, we aimed to explore the ability of I-UDSNB to differentiate between a) MCI and HC, b) AD and HC, c) MCI and AD.
methodsOne hundred thirty-seven patients (65 MCI, 72 AD) diagnosed after clinical-neuropsychological assessment, and 137 HC were included. We compared the I-UDSNB scores between a) MCI and HC, b) AD and HC, c) MCI and AD, with t-tests. To identify the test(s) most capable of differentiating between groups, significant scores were entered in binary logistic and in stepwise regressions, and then in Receiver Operating Characteristic curve analyses.
resultsTwo episodic memory tests (Craft Story and Five Words test) differentiated MCI from HC subjects; Five Words test, Semantic Fluency (vegetables), and TMT-part B differentiated AD from, respectively, HC and MCI.
conclusionsOur findings indicate that the I-UDSNB is a suitable tool for the harmonized and concise assessment of patients with cognitive decline, showing high sensitivity and specificity for the diagnosis of MCI and AD.
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