Evidence map›Paper›PMID 38704389›Full record

ArticleSpinal cord series and cases2024

Combined rehabilitation therapy with botulinum toxin to the upper limbs for acute spinal cord injury: A case report.

Haruki Mori, Gosuke Satoh, Hideki Takashima, Takashi Masuda, Tomoo Mano

Abstract readCase Reports
In one paragraph

Article in Spinal cord series and cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The use of botulinum toxin for spasticity in people with spinal cord injury: a scoping review.European journal of physical and rehabilitation medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haruki MoriDepartment of Rehabilitation, Nara Prefecture General Medical Center, Nara city, Japan.
Gosuke SatohDepartment of Rehabilitation, Nara Prefecture General Medical Center, Nara city, Japan.
Hideki TakashimaDepartment of Rehabilitation, Nara Prefecture General Medical Center, Nara city, Japan.
Takashi MasudaDepartment of Rehabilitation, Nara Prefecture General Medical Center, Nara city, Japan.
Tomoo ManoDepartment of Rehabilitation, Nara Prefecture General Medical Center, Nara city, Japan. manoneuro@naramed-u.ac.jp.ORCID 0000-0002-4788-3344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with spinal cord injury (SCI) and incomplete paralysis may experience muscle immobilization due to functional impairment of agonist and antagonist muscles. This can induce spasticity and pain, with the risk of contracture increasing as the period of immobilization increases. This could be aggravated by pain, which interferes with rehabilitation. There is no established treatment for pain and joint contractures caused by acute SCI. Botulinum therapy plays a role in relieving muscle tension. Here, we report a case of acute SCI in which botulinum therapy was administered. CASE PRESENTATION: The patient experienced a C5-cervical SCI due to a road traffic accident, with marked paralysis in the upper and lower limbs below the C5 level. The patient had persistent elbow flexion since the SCI and complained of excruciating pain, making adequate rehabilitation difficult. Botulinum toxin was administered to the biceps and brachialis muscles 15 days after the SCI. After administration, the patient experienced a reduction in pain with relaxation of the elbow flexor muscles, and rehabilitation treatment was resumed. This patient's contracture did not worsen, his pain decreased, and he was able to initiate self-feeding training. DISCUSSION: In this case, occupational and physical therapy was administered with botulinum therapy. Together, they successfully reduced pain. Botulinum therapy provides analgesia and muscle relaxation and may lead to functional recovery, and we believe that treatment can be considered even in the acute phase.

Indexed as

Spinal Cord InjuriesUpper ExtremityAdultBotulinum ToxinsBotulinum Toxins, Type ACombined Modality TherapyHumansMaleNeuromuscular AgentsBotulinum ToxinsBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID38704389
PMCPMC11069564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.