Evidence map›Paper›PMID 38703593›Full record

ReviewCancer treatment reviews2024

Salivary toxicity from PSMA-targeted radiopharmaceuticals: What we have learned and where we are going.

Miguel Muniz, Charles L Loprinzi, Jacob J Orme, Regina M Koch, Ahmed M Mahmoud, Adam M Kase, Irbaz B Riaz, Jack R Andrews, Matthew P Thorpe, Geoffrey B Johnson and 6 more

Abstract readReview
In one paragraph

Review in Cancer treatment reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Clinical research analysis of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Comparison ofEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Best Patient Care Practices for Administering PSMA-Targeted Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Miguel MunizDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, US. Electronic address: munizrincon.miguel@mayo.edu.
Charles L LoprinziDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, US. Electronic address: cloprinzi@mayo.edu.
Jacob J OrmeDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, US. Electronic address: orme.jacob@mayo.edu.
Regina M KochDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, US. Electronic address: koch.regina@mayo.edu.
Ahmed M MahmoudDepartment of Urology, Mayo Clinic, Rochester, MN, US. Electronic address: mahmoud.ahmed@mayo.edu.
Adam M KaseDepartment of Medical Oncology, Mayo Clinic, Jacksonville FL, US. Electronic address: kase.adam@mayo.edu.
Irbaz B RiazDivision of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ, US. Electronic address: riaz.irbaz@mayo.edu.
Jack R AndrewsDepartment of Urology, Mayo Clinic Arizona, Phoenix, AZ, US. Electronic address: andrews.jack@mayo.edu.
Matthew P ThorpeDepartment of Radiology, Division of Nuclear Medicine, Mayo Clinic, Rochester, MN, US. Electronic address: thorpe.matthew@mayo.edu.
Geoffrey B JohnsonDepartment of Radiology, Division of Nuclear Medicine, Mayo Clinic, Rochester, MN, US; Department of Immunology, Mayo Clinic, Rochester, MN, US. Electronic address: johnson.geoffrey@mayo.edu.
Ayse T KendiDepartment of Radiology, Division of Nuclear Medicine, Mayo Clinic, Rochester, MN, US. Electronic address: kendi.ayse@mayo.edu.
Eugene D KwonDepartment of Urology, Mayo Clinic, Rochester, MN, US. Electronic address: kwon.eugene@mayo.edu.
Jones T NauseefDivision of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY, US. Electronic address: jtn2001@med.cornell.edu.
Alicia K MorgansDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, US. Electronic address: aliciak_morgans@dfci.harvard.edu.
Oliver SartorDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, US; Department of Radiology, Division of Nuclear Medicine, Mayo Clinic, Rochester, MN, US. Electronic address: sartor.oliver@mayo.edu.
Daniel S ChildsDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, US. Electronic address: childs.daniel@mayo.edu.

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

Clinical trials of prostate-specific membrane antigen (PSMA) targeted radiopharmaceuticals have shown encouraging results. Some agents, like lutetium-177 [177Lu]Lu-PSMA-617 ([

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIRadiopharmaceuticalsDipeptidesHeterocyclic Compounds, 1-RingHumansLutetiumMaleProstatic Neoplasms, Castration-ResistantRadioisotopesSalivary GlandsAntigens, SurfaceDipeptidesFOLH1 protein, humanGlutamate Carboxypeptidase IIHeterocyclic Compounds, 1-RingLutetiumLutetium-177RadioisotopesRadiopharmaceuticalsDry mouthMetastatic castration-resistant prostate cancer (mCRPC)PSMA-targeted radiopharmaceuticalsSalivary toxicityXerostomia

Identifiers

PMID38703593
PMCPMC11160931

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.