Evidence map›Paper›PMID 38703412›Full record

ArticleJournal of molecular and cellular cardiology2024

Exercise-induced changes in myocardial glucose utilization during periods of active cardiac growth.

Kyle L Fulghum, Helen E Collins, Pawel K Lorkiewicz, Teresa A Cassel, Teresa W M Fan, Bradford G Hill

Abstract read
In one paragraph

Article in Journal of molecular and cellular cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyle L FulghumCenter for Cardiometabolic Science, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, KY, United States of America.
Helen E CollinsCenter for Cardiometabolic Science, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, KY, United States of America.
Pawel K LorkiewiczCenter for Cardiometabolic Science, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, KY, United States of America.
Teresa A CasselCenter for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States of America.
Teresa W M FanCenter for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States of America.
Bradford G HillCenter for Cardiometabolic Science, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, KY, United States of America. Electronic address: bradford.hill@louisville.edu.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
SAMPLE COREU24DK097215 · NIDDK · UNIVERSITY OF KENTUCKY · PI FAN, TERESA WHEI-MEI, HIGASHI, RICHARD M · 2013 to 2017
$8.7M
TBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI JONES, STEVEN P · 2018 to 2022
$6.3M
Biosynthetic Pathways in Cardiac RemodelingR01HL147844 · NHLBI · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY, JONES, STEVEN P · 2019 to 2022
$3.0M
Mechanisms Contributing to Pregnancy-induced Cardiac RemodelingR01HL163003 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Helen E Collins · 2023 to 2026
$2.1M
Metabolic regulation of exercise-induced adaptation in striated muscleF31HL154663 · NHLBI · UNIVERSITY OF LOUISVILLE · PI FULGHUM, KYLE · 2020 to 2022
$86k
NCI NIH HHS P30 CA177558NHLBI NIH HHS F31 HL154663NHLBI NIH HHS R01 HL147844NHLBI NIH HHS R01 HL163003NIDDK NIH HHS U24 DK097215NIEHS NIH HHS P30 ES030283NIGMS NIH HHS P30 GM127607
6 · The paper itself

Abstract

Exercise training can promote physiological cardiac growth, which has been suggested to involve changes in glucose metabolism to facilitate hypertrophy of cardiomyocytes. In this study, we used a dietary, in vivo isotope labeling approach to examine how exercise training influences the metabolic fate of carbon derived from dietary glucose in the heart during acute, active, and established phases of exercise-induced cardiac growth. Male and female FVB/NJ mice were subjected to treadmill running for up to 4 weeks and cardiac growth was assessed by gravimetry. Cardiac metabolic responses to exercise were assessed via in vivo tracing of [

Indexed as

GlucoseHeartMyocardiumPhysical Conditioning, AnimalAnimalsEnergy MetabolismFemaleMaleMiceGlucose

Identifiers

PMID38703412
PMCPMC11135805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.