Evidence map›Paper›PMID 38703388›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Long-Acting Injectable Cabotegravir and Rilpivirine in a Pregnant Woman With HIV.

Lena van der Wekken-Pas, Fabian Weiss, Charlotte Simon-Zuber, Rena Sebisch, Carmen Wiese, Elisabeth van Leeuwen, David Burger, Angela Colbers

Abstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Virologic Failure and Emergent Integrase Strand Transfer Inhibitor Drug Resistance With Long-Acting Cabotegravir for HIV Treatment: A Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lena van der Wekken-PasDepartment of Pharmacy, Radboud University Medical Center, Radboud Institute for Medical Innovations (RIMI), Nijmegen, The Netherlands.ORCID 0000-0001-8674-1448
Fabian WeissDepartment of Obstetrics and Gynecology, LMU University Hospital, Munich, Germany.
Charlotte Simon-ZuberDepartment of Obstetrics and Gynecology, LMU University Hospital, Munich, Germany.
Rena SebischDepartment of Obstetrics and Gynecology, LMU University Hospital, Munich, Germany.
Carmen WieseDepartment of Internal Medicine, MVZ München am Goetheplatz, Munich, Germany.
Elisabeth van LeeuwenDepartment of Gynecology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
David BurgerDepartment of Pharmacy, Radboud University Medical Center, Radboud Institute for Medical Innovations (RIMI), Nijmegen, The Netherlands.
Angela ColbersDepartment of Pharmacy, Radboud University Medical Center, Radboud Institute for Medical Innovations (RIMI), Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes the effects of bimonthly long-acting injectable cabotegravir (CAB)/RPV before and throughout pregnancy. CAB concentrations were comparable to those in nonpregnant individuals; RPV concentrations were 70%-75% lower. No virologic failure or vertical transmission occurred. Despite placental transfer, no congenital malformations were noted. Bimonthly long-acting injectable CAB/RPV may not be suitable for pregnant women, and monitoring of exposed infants is warranted.

Indexed as

Anti-HIV AgentsHIV InfectionsPregnancy Complications, InfectiousPyridonesRilpivirineAdultDiketopiperazinesFemaleHumansPregnancyAnti-HIV AgentscabotegravirDiketopiperazinesPyridonesRilpivirinecabotegravirHIVlong-acting injectablespregnancyrilpivirine

Identifiers

PMID38703388
PMCPMC11650856

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.