Evidence map›Paper›PMID 38703067›Full record

ArticleThe Journal of urology2024

Lower Urinary Tract Symptoms in US Women: Contemporary Prevalence Estimates from the RISE FOR HEALTH Study.

Siobhan Sutcliffe, Chloe Falke, Cynthia S Fok, James W Griffith, Bernard L Harlow, Kimberly A Kenton, Cora E Lewis, Lisa Kane Low, Jerry L Lowder, Emily S Lukacz and 12 more

Abstract read
In one paragraph

Article in The Journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Siobhan SutcliffeDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-4613-8107
Chloe FalkeDivision of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, Minnesota.
Cynthia S FokDepartment of Urology and the Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
James W GriffithDepartment of Medical Social Sciences, Northwestern University, Chicago, Illinois.
Bernard L HarlowDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Kimberly A KentonSection of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois.
Cora E LewisDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Lisa Kane LowSchool of Nursing, University of Michigan, Ann Arbor, Michigan.
Jerry L LowderDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Emily S LukaczDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California.
Alayne D MarklandDivision of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, University of Alabama at Birmingham, and the Geriatric Research, Education, and Clinical Center at the Birmingham Veterans Affairs Health Care System, Birmingham, Alabama.
Gerald McGwinDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Melanie R MeisterDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas.
Elizabeth R MuellerDepartments of Obstetrics and Gynecology, and Urology, Loyola University Medical Center, Loyola University Chicago, Chicago, Illinois.
Diane K NewmanDivision of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Ratna PakpahanDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Leslie M RickeyDepartment of Urology and the Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.
Todd RockwoodDivision of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, Minnesota.
Melissa A SimonDivision of General Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Abigail R SmithDivision of Biostatistics, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Kyle D RudserDivision of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, Minnesota.
Ariana L SmithDivision of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Scientific and Data Coordinating CenterU24DK106786 · NIDDK · UNIVERSITY OF MINNESOTA · PI MCGWIN, GERALD, RUDSER, KYLE · 2020 to 2024
$7.1M
University of Pennsylvania+ PLUS Clinical Center (PENN+PLUS CC)U01DK106892 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI NEWMAN, DIANE K., SMITH, ARIANA L · 2015 to 2024
$5.4M
PLUS Loyola Clinical CenterU01DK106898 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, FITZGERALD, COLLEEN MARIE · 2015 to 2024
$4.7M
Prevention of LUTS: Bladder Health Clinical Center, UC San Diego SiteU01DK106827 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACOURSIERE, DAPHNE YVETTE, LUKACZ, EMILY S. · 2015 to 2024
$4.5M
Pathways to LUTS Prevention: A Model for Public Education, Behavioral Skills, and Early DetectionU01DK106858 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCGWIN, GERALD · 2015 to 2024
$4.5M
LUTS PREVENTION IN ADOLESCENT GIRLS AND WOMEN ACROSS THE LIFESPANU01DK106853 · NIDDK · WASHINGTON UNIVERSITY · PI SUTCLIFFE, SIOBHAN · 2015 to 2024
$4.0M
The Truly Healthy Bladder: Understanding Normal As A Pathway To Prevention Of Lower Urinary Tract Symptoms In WomenU01DK106893 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOW, LISA KANE · 2015 to 2024
$3.8M
Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Yale Clinical Research CenterU01DK106908 · NIDDK · YALE UNIVERSITY · PI RICKEY, LESLIE M. · 2015 to 2024
$3.5M
NORTHWESTERN UNIVERSITY PLUS CLINICAL SITEU01DK126045 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GRIFFITH, JAMES WILLIAM, SIMON, MELISSA A. · 2020 to 2024
$1.4M
Research and Mentoring Program in Improving Access to Incontinence Care for Older AdultsK24AG073586 · NIA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Alayne Denise Markland · 2022 to 2026
$619k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K24 AG073586NIDDK NIH HHS U01 DK106827NIDDK NIH HHS U01 DK106853NIDDK NIH HHS U01 DK106858NIDDK NIH HHS U01 DK106892NIDDK NIH HHS U01 DK106893NIDDK NIH HHS U01 DK106898NIDDK NIH HHS U01 DK106908NIDDK NIH HHS U01 DK126045NIDDK NIH HHS U24 DK106786
6 · The paper itself

Abstract

purposeWe aimed to estimate the prevalence of a wide range of lower urinary tract symptoms (LUTS) in US women, and explore associations with bother and discussion with health care providers, friends, and family. MATERIALS AND

methodsWe analyzed baseline data collected from May 2022 to December 2023 in the RISE FOR HEALTH study-a large, regionally representative cohort study of adult female community members. LUTS and related bother were measured by the 10-item Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index, and discussion was assessed by a study-specific item.

resultsOf the 3000 eligible participants, 73% (95% CI 71%-74%) reported any storage symptoms, 52% (95% CI 50%-53%) any voiding or emptying symptoms, and 11% (95% CI 10%-13%) any pain with bladder filling, for an overall LUTS prevalence of 79% (95% CI 78%-81%). This prevalence estimate included 43% (95% CI 41%-45%) of participants with mild to moderate symptoms and 37% (95% CI 35%-38%) with moderate to severe symptoms. Over one-third of participants reported LUTS-related bother (38%, 95% CI 36%-39%) and discussion (38%, 95% CI 36%-40%), whereas only 7.1% (95% CI 6.2%-8.1%) reported treatment. Urgency and incontinence (including urgency and stress incontinence) were associated with the greatest likelihood of bother and/or discussion (adjusted prevalence ratios = 1.3-2.3), even at mild to moderate levels. They were also the most commonly treated LUTS.

conclusionsLUTS, particularly storage LUTS such as urgency and incontinence, were common and bothersome in the RISE study population, yet often untreated. Given this large burden, both prevention and treatment-related interventions are warranted to reduce the high prevalence and bother of LUTS.

Indexed as

Lower Urinary Tract SymptomsAdultAgedCohort StudiesFemaleHumansMiddle AgedPrevalenceUnited Statesepidemiologyfemalelower urinary tract symptoms

Identifiers

PMID38703067
PMCPMC11166514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.