Evidence map›Paper›PMID 38702638›Full record

ArticleBMC pediatrics2024

Impulse oscillometry in the diagnosis of cough variant asthma in children.

Chunyu Tian, Shiqiu Xiong, Shuo Li, Xin Song, Yantao Zhang, Xinmei Jiang, Xinyue Hou, Yifan Zhang, Chuanhe Liu

Abstract read
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunyu TianDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Shiqiu XiongDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Shuo LiDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Xin SongDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Yantao ZhangDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Xinmei JiangDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Xinyue HouDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Yifan ZhangDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China.
Chuanhe LiuDepartment of Allergy, Children's Hospital Affiliated with the Capital Institute of Pediatrics, No.2 Yabao Road, Chaoyang District, Beijing, 100020, China. liuchcip@126.com.

Funding

the Capital Institute of Pediatrics Foundation PY-2019-12
6 · The paper itself

Abstract

backgroundCough variant asthma (CVA) is one of the most common causes of chronic cough in children worldwide. The diagnosis of CVA in children remains challenging. This study aimed to assess the diagnostic utility of impulse oscillometry (IOS) pulmonary function in children with CVA.

methodsThis study included children aged 4 to 12 years diagnosed with CVA who underwent IOS pulmonary function and bronchodilation (BD) tests. A control group of healthy children was matched. Pre- and post-BD IOS parameters were recorded and presented as mean ± standard deviation or median. Receiver operating characteristic (ROC) curves were plotted, and the area under the curve (AUC) was calculated to evaluate the discriminatory potential of the IOS parameters for diagnosing CVA.

resultsA total of 180 patients with CVA and 65 control subjects were included. The baseline IOS parameters in the CVA group, except X5%pred, were significantly greater compared to the control group. After inhalation of salbutamol sulfate, all IOS parameters improved significantly in the CVA group. However, Z5%pred, R5%pred, and R20%pred remained greater in the CVA group compared to the control group. The improvement rates of IOS parameters in the CVA group significantly surpassed those in the control group. The ROC curve results for pre-BD IOS parameters and the improvement rate during the BD test showed that the combinations of pre-Z5%pred+

conclusionsThis study highlights that children with CVA exhibit greater IOS parameters compared to healthy children. The changes in IOS parameters during the BD test provided valuable diagnostic information for CVA, and the combination of various parameters can help pediatricians accurately identify CVA in children.

Indexed as

Cough-Variant AsthmaOscillometryAlbuterolBronchodilator AgentsCase-Control StudiesChildChild, PreschoolCoughFemaleHumansMaleRespiratory Function TestsROC CurveAlbuterolBronchodilator AgentsChildrenCough variant asthmaDiagnosisImpulse oscillometry

Identifiers

PMID38702638
PMCPMC11067131

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.