Evidence map›Paper›PMID 38702630›Full record

ArticleBMC immunology2024

Atypical memory B cells increase in the peripheral blood of patients with breast cancer regardless of lymph node involvement.

Atefeh Azizi, Fereshteh Mehdipour, Morteza Samadi, Reza Rasolmali, Abdol-Rasoul Talei, Abbas Ghaderi

Abstract read
In one paragraph

Article in BMC immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Atefeh AziziDepartment of Immunology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Fereshteh MehdipourShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. mehdipourf@sums.ac.ir.
Morteza SamadiDepartment of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. samadi.for@gmail.com.
Reza RasolmaliDepartment of Pathology, Shiraz Central Hospital, Shiraz, Iran.
Abdol-Rasoul TaleiBreast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Abbas GhaderiShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

Shahid Sadoughi University of Medical Sciences 15098Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences ICR-100-508
6 · The paper itself

Abstract

backgroundBreast cancer is the most common cancer in females. The immune system has a crucial role in the fight against cancer. B and T cells, the two main components of the adaptive immunity, are critical players that specifically target tumor cells. However, B cells, in contrast to T cells, and their role in cancer inhibition or progression is less investigated. Accordingly, in this study, we assessed and compared the frequency of naïve and different subsets of memory B cells in the peripheral blood of patients with breast cancer and healthy women.

resultsWe found no significant differences in the frequencies of peripheral CD19

conclusionAtypical memory B cells (CD19

Indexed as

Breast NeoplasmsLymph NodesMemory B CellsAdultAgedAntigens, CD19B-Lymphocyte SubsetsFemaleHumansImmunologic MemoryMiddle AgedTumor Necrosis Factor Receptor Superfamily, Member 7Antigens, CD19Tumor Necrosis Factor Receptor Superfamily, Member 7Atypical memory B cellsB cellsBreast cancerPeripheral blood mononuclear cells

Identifiers

PMID38702630
PMCPMC11067195

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.