Evidence map›Paper›PMID 38702448›Full record

ArticleAnalytical and bioanalytical chemistry2024

Simple and sensitive galactose monitoring based on capillary SERS sensor.

Eun Hae Heo, Hyejin Chang

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eun Hae HeoDivision of Science Education, Kangwon National University, Chuncheon, 24341, Republic of Korea.
Hyejin ChangDivision of Science Education, Kangwon National University, Chuncheon, 24341, Republic of Korea. hjchang@kangwon.ac.kr.ORCID http://orcid.org/0000-0003-0569-4155

Funding

Korea Basic Science Institute 2020R1A6C101A195National Research Foundation of Korea NRF-2021R1C1C1011739
6 · The paper itself

Abstract

Galactosemia, a severe genetic metabolic disorder, results from the absence of galactose-degrading enzymes, leading to harmful galactose accumulation. In this study, we introduce a novel capillary-based surface-enhanced Raman spectroscopy (SERS) sensor for convenient and sensitive galactose detection. The developed sensor enhances SERS signals by introducing gold nanoparticles (Au NPs) onto the surface of silver nanoshells (Ag NSs) within a capillary, creating Ag NSs with Au NPs as satellites. Utilizing 4-mercaptophenylboronic acid (4-MPBA) as a Raman reporter molecule, the detection method relies on the conversion of 4-MPBA to 4-mercaptophenol (4-MPhOH) driven by hydrogen peroxide (H

Indexed as

GalactoseGoldMetal NanoparticlesSilverSpectrum Analysis, RamanBiosensing TechniquesBoronic AcidsGalactosemiasGalactose OxidaseHumansHydrogen PeroxideLimit of DetectionSulfhydryl Compounds4-mercaptophenylboronic acidBoronic AcidsGalactoseGalactose OxidaseGoldHydrogen PeroxideSilverSulfhydryl Compounds4-Mercaptophenylboronic acidCapillary sensorCore-satellite nanostructuresGalactose detectionSurface-enhanced Raman spectroscopy

Identifiers

PMID38702448

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.