Evidence map›Paper›PMID 38702411›Full record

ArticleScientific reports2024

Chronicling menstrual cycle patterns across the reproductive lifespan with real-world data.

Adam C Cunningham, Lubna Pal, Aidan P Wickham, Carley Prentice, Frederick G B Goddard, Anna Klepchukova, Liudmila Zhaunova

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam C CunninghamFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK. a_cunningham@flo.health.ORCID 0000-0002-9791-7813
Lubna PalDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Aidan P WickhamFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK.
Carley PrenticeFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK.
Frederick G B GoddardFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK.
Anna KlepchukovaFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK.
Liudmila ZhaunovaFlo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The intricate hormonal and physiological changes of the menstrual cycle can influence health on a daily basis. Although prior studies have helped improve our understanding of the menstrual cycle, they often lack diversity in the populations included, sample size, and the span of reproductive and life stages. This paper aims to describe the dynamic differences in menstrual cycle characteristics and associated symptoms by age in a large global cohort of period-tracking application users. This work aims to contribute to our knowledge and understanding of female physiology at varying stages of reproductive aging. This cohort study included self-reported menstrual cycle and symptom information in a sample of Flo application users aged 18-55. Cycle and period length and their variability, and frequency of menstrual cycle symptom logs are described by the age of the user. Based on data logged by over 19 million global users of the Flo app, the length of the menstrual cycle and period show clear age-associated patterns. With higher age, cycles tend to get shorter (Cycle length:

Indexed as

Menstrual CycleAdolescentAdultAge FactorsAgingCohort StudiesFemaleHumansMiddle AgedReproductionSelf ReportYoung AdultDigital healthHealth literacyMenstrual cyclePeriod tracking appReproductive agingWomen’s health

Identifiers

PMID38702411
PMCPMC11068910

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.