Evidence map›Paper›PMID 38702323›Full record

ArticleCell death discovery2024

IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis.

Yunyi Nan, Minhao Chen, Weijie Wu, Rongrong Huang, Weiwei Sun, Qian Lu, Zhifeng Gu, Xingxing Mao, Hua Xu, Youhua Wang

Abstract read
In one paragraph

Article in Cell death discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Deficiency of the mCellular and molecular life sciences : CMLS · 2026
    Article
  4. Article
  5. Nanozyme-Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Crosstalk between N6-methyladenosine modification and ncRNAs in rheumatic diseases: therapeutic and diagnostic implications.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yunyi Nan *Department of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China.
Minhao Chen *Department of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China.
Weijie Wu *Department of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China.
Rongrong HuangDepartment of Pharmacy, Affiliated Hospital of Nantong University, 226001, Nantong, China.ORCID http://orcid.org/0000-0002-9730-7898
Weiwei SunDepartment of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China.
Qian LuDepartment of Rheumatology, Affiliated Hospital of Nantong University, 226001, Nantong, China.
Zhifeng GuDepartment of Rheumatology, Affiliated Hospital of Nantong University, 226001, Nantong, China.
Xingxing MaoDepartment of Orthopaedics, Affiliated Nantong Hospital of Shanghai University, The Sixth People's Hospital of Nantong, 226001, Nantong, China. 15152882182@139.com.ORCID http://orcid.org/0009-0003-5267-7857
Hua XuDepartment of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China. xuhua1981111@126.com.ORCID http://orcid.org/0000-0002-7969-6033
Youhua WangDepartment of Orthopaedics, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001, Nantong, China. wangyouhua99@163.com.ORCID http://orcid.org/0000-0002-2100-3046

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82072395
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease with an unknown etiology. RA cannot be fully cured and requires lengthy treatment, imposing a significant burden on both individuals and society. Due to the lack of specific drugs available for treating RA, exploring a key new therapeutic target for RA is currently an important task. Activated fibroblast-like synoviocytes (FLSs) play a crucial role in the progression of RA, which release interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α resulting in abnormal inflammatory reaction in the synovium. A previous study has highlighted the correlation of m

Identifiers

PMID38702323
PMCPMC11068746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.