Evidence map›Paper›PMID 38702305›Full record

ArticleNPJ Parkinson's disease2024

Misfolded protein deposits in Parkinson's disease and Parkinson's disease-related cognitive impairment, a [

Michele Matarazzo, Alexandra Pérez-Soriano, Nasim Vafai, Elham Shahinfard, Kevin Ju-Chieh Cheng, Jessamyn McKenzie, Nicole Neilson, Qing Miao, Paul Schaffer, Hitoshi Shinotoh and 3 more

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. PET imaging of alpha-synuclein: from radiotracer design through in vitro and in vivo translation.European journal of nuclear medicine and molecular imaging · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michele MatarazzoDjavad Mowafaghian Centre for Brain Health, Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-2907-8667
Alexandra Pérez-SorianoDjavad Mowafaghian Centre for Brain Health, Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, BC, Canada.
Nasim VafaiDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.
Elham ShahinfardDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-3526-0086
Kevin Ju-Chieh ChengDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.
Jessamyn McKenzieDjavad Mowafaghian Centre for Brain Health, Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, BC, Canada.
Nicole NeilsonDjavad Mowafaghian Centre for Brain Health, Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, BC, Canada.
Qing MiaoTRIUMF, Vancouver, BC, Canada.
Paul SchafferTRIUMF, Vancouver, BC, Canada.
Hitoshi ShinotohDepartment of Functional Brain Imaging Research, National Institute of Radiological Sciences, Chiba, Japan.
Jeffrey H KordowerASU-Banner Neurodegenerative Disease Research Center and School of Life Sciences, Arizona State University, Tempe, AZ, USA.ORCID http://orcid.org/0000-0001-8629-3294
Vesna SossiDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0001-7862-5711
A Jon StoesslDjavad Mowafaghian Centre for Brain Health, Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, BC, Canada. jon.stoessl@ubc.ca.ORCID http://orcid.org/0000-0002-9778-7246

Funding

Weston Brain Institute TR140116
6 · The paper itself

Abstract

Parkinson's disease (PD) is associated with aggregation of misfolded α-synuclein and other proteins, including tau. We designed a cross-sectional study to quantify the brain binding of [

Identifiers

PMID38702305
PMCPMC11068893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.