Evidence map›Paper›PMID 38702075›Full record

ArticleLife science alliance2024

Systems genetics analysis of human body fat distribution genes identifies adipocyte processes.

Jordan N Reed, Jiansheng Huang, Yong Li, Lijiang Ma, Dhanush Banka, Martin Wabitsch, Tianfang Wang, Wen Ding, Johan Lm Björkegren, Mete Civelek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Distinct blood transcriptomic profiling underlying asthma establishment and exacerbation.The journal of allergy and clinical immunology. Global · 2026
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jordan N ReedDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-6190-9037
Jiansheng HuangNovo Nordisk Research Center China, Novo Nordisk A/S, Beijing, China.
Yong LiNovo Nordisk Research Center China, Novo Nordisk A/S, Beijing, China.
Lijiang MaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Dhanush BankaDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Martin WabitschDivision of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine, Ulm University Medical Centre, Ulm, Germany.ORCID 0000-0001-6795-8430
Tianfang WangNovo Nordisk Research Center China, Novo Nordisk A/S, Beijing, China.
Wen DingNovo Nordisk Research Center China, Novo Nordisk A/S, Beijing, China.
Johan Lm BjörkegrenDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mete CivelekDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA mete@virginia.edu.ORCID 0000-0002-8141-0284

Funding

BASIC CARDIOVASCULAR RESEARCH TRAINING GRANTT32HL007284 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Brant E Isakson, Gary K Owens · 1985 to 2026
$19.6M
The role of adipocyte KLF14 in Metabolic SyndromeR01DK118287 · NIDDK · UNIVERSITY OF VIRGINIA · PI CIVELEK, METE · 2018 to 2022
$2.4M
NHLBI NIH HHS T32 HL007284NIDDK NIH HHS R01 DK118287
6 · The paper itself

Abstract

Excess abdominal fat is a sexually dimorphic risk factor for cardio-metabolic disease and is approximated by the waist-to-hip ratio adjusted for body mass index (WHR

Indexed as

AdipocytesAdipogenesisBody Fat DistributionAdipose TissueAdultBayes TheoremBody Mass IndexFemaleGene Expression RegulationGene Regulatory NetworksHumansMaleMiddle AgedSystems BiologyWaist-Hip RatioWnt Signaling Pathway

Identifiers

PMID38702075
PMCPMC11068934

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.