Evidence map›Paper›PMID 38702070›Full record

ArticleBMJ case reports2024

Polymyxin B-induced Bartter syndrome.

Bhavesh Mohan Lal, Nimisha Musthafa Hafeesa, Naval Kishore Vikram, Animesh Ray

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bhavesh Mohan LalDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Nimisha Musthafa HafeesaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Naval Kishore VikramDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Animesh RayDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India doctoranimeshray@gmail.com.ORCID http://orcid.org/0000-0001-7498-9112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bartter syndrome is a genetic disorder characterised by chloride-unresponsive metabolic alkalosis, hypokalaemia, hypomagnesaemia and hypercalciuria. While it commonly presents antenatally or in early infancy, sometimes, drugs can induce a state similar to Bartter syndrome in any age group, called acquired Bartter syndrome. Polymyxins and aminoglycosides are the most commonly implicated drugs. Polymyxin B and polymyxin E (popularly known as colistin) are the two chemically similar polymyxins that are commonly used clinically. While colistin is frequently associated with nephrotoxicity, polymyxin B is generally considered less nephrotoxic. This difference is due to the way these two drugs are handled by the kidneys. In this case report, we discuss a middle-aged male who developed Bartter syndrome due to polymyxin B, which resolved on discontinuation of the drug, and re-appeared after its re-introduction later. This case exemplifies the nephrotoxicity caused by polymyxin B and the need for vigilance when using this drug.

Indexed as

Anti-Bacterial AgentsBartter SyndromePolymyxin BHumansMaleMiddle AgedAnti-Bacterial AgentsPolymyxin BAdult intensive careDrugs: infectious diseasesFluid electrolyte and acid-base disturbancesUnwanted effects / adverse reactions

Identifiers

PMID38702070
PMCPMC11085949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.