Evidence map›Paper›PMID 38702054›Full record

ArticleDiabetes & vascular disease research

Association between gamma glutamyl transpeptidase to HDL-Cholesterol (GGT/HDL-C) ratio and metabolic syndrome resolution after sleeve gastrectomy.

Melanni L Lizarbe-Lezama, Jhoel E Rodriguez-Macedo, Daniel Fernandez-Guzman, Ana L Alcantara-Diaz, Gustavo Salinas-Sedo, Carlos J Toro-Huamanchumo

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Article in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Melanni L Lizarbe-LezamaSchool of Medicine, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Jhoel E Rodriguez-MacedoSchool of Medicine, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Daniel Fernandez-GuzmanUniversidad Científica del Sur, Lima, Peru.
Ana L Alcantara-DiazOBEMET Center for Obesity and Metabolic Health, Lima, Peru.
Gustavo Salinas-SedoClínica Avendaño, Lima, Peru.
Carlos J Toro-HuamanchumoOBEMET Center for Obesity and Metabolic Health, Lima, Peru.ORCID 0000-0002-4664-2856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association between GGT/HDL-C ratio and resolution of MetS in adults after sleeve gastrectomy (SG).

methodsWe conducted a retrospective cohort study using secondary data from a Peruvian bariatric center. The study population consisted of adults aged 18 and above who underwent laparoscopic SG and were diagnosed with MetS prior to the surgery. The main outcome measured was MetS resolution 6 months post-surgery and the exposure variable was the GGT/HDL-C ratio.

resultsWe analyzed 137 patients with a mean age of 38.9 ± 10.9 years; 64.2% were females. The median GGT/HDL-C ratio was 1.1 [0.7 - 1.5], and 83.9% of patients experienced resolution of MetS. Furthermore, both the middle tertile of GGT/HDL-C (aRR: 1.28; 95% CI: 1.04 - 1.58;

conclusionEight out of 10 patients undergoing SG experience resolution of MetS within 6 months after surgery. Patients in the middle and lower tertiles of the GGT/HDL-C were more likely to achieve this outcome. Therefore, the GGT/HDL-C ratio should be considered a valuable and efficient biomarker for preoperative assessment of bariatric surgery candidates.

Indexed as

BiomarkersCholesterol, HDLgamma-GlutamyltransferaseGastrectomyMetabolic SyndromeAdultBariatric SurgeryFemaleHumansLaparoscopyMaleMiddle AgedObesity, MorbidPeruPredictive Value of TestsRemission InductionBiomarkersCholesterol, HDLgamma-Glutamyltransferasegamma-glutamyltransferase, humanbariatric surgerycholesterolgamma-GlutamyltransferaseHDL (MeSH-NLM)lipoproteinsMetabolic syndromeobesity

Identifiers

PMID38702054
PMCPMC11069333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.