Evidence map›Paper›PMID 38701023›Full record

ArticleGenome biology and evolution2024

Unveiling the Genetic Blueprint of a Desert Scorpion: A Chromosome-level Genome of Hadrurus arizonensis Provides the First Reference for Parvorder Iurida.

Meridia Jane Bryant, Asher M Coello, A M Glendening, Samuel A Hilliman, Carolina Fernanda Jara, Samuel S Pring, Aviel Rodríguez Rivera, Jennifer Santiago Membreño, Lisa Nigro, Nicole Pauloski and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome biology and evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Meridia Jane BryantDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0003-0651-8970
Asher M CoelloDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0001-7917-338X
A M GlendeningDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0002-0508-6547
Samuel A HillimanDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0006-9992-436X
Carolina Fernanda JaraDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0006-3451-3228
Samuel S PringDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0004-4539-3984
Aviel Rodríguez RiveraDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0006-4694-4199
Jennifer Santiago MembreñoDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0001-6739-7829
Lisa NigroInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0000-0003-1801-2360
Nicole PauloskiDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.ORCID 0009-0004-6135-7078
Matthew R GrahamDepartment of Biology, Eastern Connecticut State University, Willimantic, CT, USA.ORCID 0000-0001-7192-1083
Teisha KingDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0003-3073-5596
Elizabeth L JockuschDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0003-4718-0531
Rachel J O'NeillDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-1525-6821
Jill L WegrzynDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0001-5923-0888
Carlos E Santibáñez-LópezDepartment of Biology, Western Connecticut State University, Danbury, CT, USA.ORCID 0000-0001-6062-282X
Cynthia N WebsterDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-8646-1398

Funding

National Science Foundation DBI-1943371
6 · The paper itself

Abstract

Over 400 million years old, scorpions represent an ancient group of arachnids and one of the first animals to adapt to life on land. Presently, the lack of available genomes within scorpions hinders research on their evolution. This study leverages ultralong nanopore sequencing and Pore-C to generate the first chromosome-level assembly and annotation for the desert hairy scorpion, Hadrurus arizonensis. The assembled genome is 2.23 Gb in size with an N50 of 280 Mb. Pore-C scaffolding reoriented 99.6% of bases into nine chromosomes and BUSCO identified 998 (98.6%) complete arthropod single copy orthologs. Repetitive elements represent 54.69% of the assembled bases, including 872,874 (29.39%) LINE elements. A total of 18,996 protein-coding genes and 75,256 transcripts were predicted, and extracted protein sequences yielded a BUSCO score of 97.2%. This is the first genome assembled and annotated within the family Hadruridae, representing a crucial resource for closing gaps in genomic knowledge of scorpions, resolving arachnid phylogeny, and advancing studies in comparative and functional genomics.

Indexed as

GenomeScorpionsAnimalsChromosomesEvolution, MolecularMolecular Sequence AnnotationPhylogenyarachnidHadruridaenanoporepore-creference genomescorpion

Identifiers

PMID38701023
PMCPMC11126328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.