Evidence map›Paper›PMID 38700763›Full record

ArticleProbiotics and antimicrobial proteins2025

Probiotic Characteristics of Lactiplantibacillus plantarum CECT 9435 and Its Survival and Competitive Properties Under Simulated Conditions of the Child Gut Microbiota.

Teresa Requena, M Carmen Martínez-Cuesta, Rosa Aznar, M Luz Mohedano, Paloma López, Patricia Ruas-Madiedo

Abstract read
In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Therapeutic potential of the probioticCurrent research in food science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teresa RequenaDepartment of Food Biotechnology and Microbiology, BFBL Group, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC, Madrid, Spain. t.requena@csic.es.
M Carmen Martínez-CuestaDepartment of Food Biotechnology and Microbiology, BFBL Group, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC, Madrid, Spain.
Rosa AznarDepartment of Microbiology and Ecology and Spanish Collection of Type Cultures (CECT), University of Valencia, Valencia, Spain.
M Luz MohedanoDepartment of Microorganisms and Plant Biotechnology, Margarita Salas Center for Biological Research (CIB), CSIC, Madrid, Spain.
Paloma LópezDepartment of Microorganisms and Plant Biotechnology, Margarita Salas Center for Biological Research (CIB), CSIC, Madrid, Spain.
Patricia Ruas-MadiedoMicroHealth Group, Instituto de Productos Lácteos de Asturias (IPLA), CSIC, Villaviciosa, Asturias, Spain.

Funding

CYTED Ciencia y Tecnología para el Desarrollo 917PTE0537Ministerio de Ciencia e Innovación PCIN2017-003Ministerio de Ciencia e Innovación PCIN2017-075
6 · The paper itself

Abstract

Probiotics are valuable microorganisms effective in reducing malnutrition-related infections in children. In this work, a collection of lactobacilli strains representative of traditional Andean fermented beverages was in vitro screened for their capability to survive the gastrointestinal transit, to adhere to the intestinal epithelium and to compete under simulated conditions of the child gut microbiota. The results allowed the selection of the riboflavin overproducing strain Lactiplantibacillus plantarum CECT 9435 based on its good rate of survival under in vitro gastrointestinal conditions when included in a food matrix representing the fortified food supplement Incaparina. The strain also showed good adhesion to HT29 cells producing mucus and outstanding performance in E. coli competition for the adhesion to this epithelial cell line. L. plantarum CECT 9435 gut performance was also evaluated in the child intestinal microbiota simulated in a dynamic gut model (BFBL simulator). The viability of the probiotic candidate in the gut conditions was high during the 7-day intervention period, reaching over 1 × 10

Indexed as

Gastrointestinal MicrobiomeLactiplantibacillus plantarumProbioticsBacterial AdhesionChildEscherichia coliHT29 CellsHumansMicrobial ViabilityChild gut microbiotaFortified foodHT29Lactiplantibacillus plantarumProbiotic

Identifiers

PMID38700763
PMCPMC12405041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.