ArticleSurgery today2024
Prognostic value of perioperative changes in the prognostic nutritional index in patients with surgically resected non-small cell lung cancer.
Article in Surgery today, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between the prognostic nutritional index and prognosis in patients with non-small cell lung cancer undergoing curative lung resection: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Prognostic effect of the pretreatment prognostic nutritional index in cervical, ovarian, and endometrial cancer: a meta-analysis.BMC women's health · 2024Pooled it
- The merits of the prognostic nutritional index and neutrophil-to-lymphocyte ratio in predicting outcomes of coronary artery bypass grafting: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Osteosarcopenia as a prognostic indicator of gastric cancer compared with established nutritional markers.Langenbeck's archives of surgery · 2026Article
- Variability of the prognostic nutritional index within 3 months after curative resection for non-small cell lung cancer and 2-year recurrence-free survival.BMC pulmonary medicine · 2026Article
- Association between diaphragm thickness and postoperative complications in elderly patients with non-small-cell lung cancer.Surgery today · 2026Article
- Multidimensional modeling and stratification of nutritional risk in non-small cell lung cancer based on artificial intelligence-derived CT body composition phenotypes.Frontiers in nutrition · 2026Article
- Preoperative pulmonary function and nutrition predict survival in lung cancer patients with previous operated malignancies.Journal of thoracic disease · 2025Article
- Recurrence Pattern of Left Upper Lobectomies and Trisegmentectomies: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Postoperative pneumonia in patients with non-small cell lung cancer undergoing thoracoscopic surgery: What should we care about?Frontiers in oncology · 2025Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis single-institution retrospective cohort study was conducted to assess the prognostic significance of perioperative changes in the prognostic nutritional index (PNI) in patients who underwent surgery for non-small cell lung cancer (NSCLC).
methodsClinicopathological data were collected from 441 patients who underwent lobectomy for NSCLC between 2010 and 2016.The PNI ratio (postoperative PNI/preoperative PNI) was used as an indicator of perioperative PNI changes. Prognostic differences were investigated based on PNI ratios.
resultsThe optimal cut-off value of the PNI ratio for overall survival (OS) was set at 0.88 using a receiver operating characteristic curve. The PNI ratio was inversely related to a high smoking index, interstitial lung disease, and postoperative pulmonary complications. The 5-year OS rates for the high vs. low PNI ratio groups were 88.2% vs. 68.5%, respectively (hazard ratio [HR]: 3.04, 95% confidence interval [CI]: 1.90-4.86). Multivariable analysis revealed that a low PNI ratio was significantly associated with poor prognosis (HR: 2.94, 95% CI: 1.77-4.87). The PNI ratio was a more sensitive indicator than postoperative PNI status alone for identifying patients at high risk of mortality, particularly those with non-lung cancer causes.
conclusionThe perioperative PNI change is a significant prognostic factor for patients with NSCLC.
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