Evidence map›Paper›PMID 38700571›Full record

ArticleCell biology and toxicology2024

Exosomal YB-1 facilitates ovarian restoration by MALAT1/miR-211-5p/FOXO

Mengxue Zhang, Jie Xing, Shijie Zhao, Minjun Lu, Yueqin Liu, Li Lin, Wujiang Gao, Lu Chen, Wenxin Li, Junyu Shang and 3 more

Abstract read
In one paragraph

Article in Cell biology and toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. NcRNAs: a potential treatment for spinal cord injury.Frontiers in cellular neuroscience · 2025
    Review
  8. Long Noncoding RNA MALAT1: Salt-Sensitive Hypertension.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mengxue Zhang *Reproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Jie Xing *Reproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Shijie Zhao *Reproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Minjun LuReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Yueqin LiuReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Li LinReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Wujiang GaoReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Lu ChenReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Wenxin LiReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Junyu ShangReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Jiamin ZhouReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China.
Xinming YinDepartment of Central Laboratory, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, People's Republic of China.
Xiaolan ZhuReproductive Center, The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, People's Republic of China. zxl2517@163.com.

Funding

City Social Development Project of Zhenjiang SH2023057/SH2022060Jiangsu Provincial Health Commission Medical Research Key Project K2023078National Natural Science Foundation of China 82172838Science and Technology Bureau of Zhenjiang SH 2022048
6 · The paper itself

Abstract

Premature ovarian failure (POF) affects many adult women less than 40 years of age and leads to infertility. Mesenchymal stem cells-derived small extracellular vesicles (MSCs-sEVs) are attractive candidates for ovarian function restoration and folliculogenesis for POF due to their safety and efficacy, however, the key mediator in MSCs-sEVs that modulates this response and underlying mechanisms remains elusive. Herein, we reported that YB-1 protein was markedly downregulated in vitro and in vivo models of POF induced with H

Indexed as

ExosomesForkhead Box Protein O3Granulosa CellsMesenchymal Stem CellsMicroRNAsPrimary Ovarian InsufficiencyRNA, Long NoncodingY-Box-Binding Protein 1AnimalsCellular SenescenceDNA-Binding ProteinsFemaleHumansOvaryRatsRats, Sprague-DawleyDNA-Binding ProteinsForkhead Box Protein O3FOXO3 protein, humanFOXO3 protein, ratMALAT1 long non-coding RNA, humanMALAT1 long noncoding RNA, ratMicroRNAsMIRN211 microRNA, humanRNA, Long NoncodingY-Box-Binding Protein 1YBX1 protein, humanYbx1 protein, ratMALAT1POFsEVsYB-1

Identifiers

PMID38700571
PMCPMC11068691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.