Evidence map›Paper›PMID 38700554›Full record

ArticlePediatric radiology2024

Photon-counting computed tomography for paediatric congenital heart defects yields images of high diagnostic quality with low radiation doses at both 70 kV and 90 kV.

Fredrik Stålhammar, Marie-Louise Aurumskjöld, Sofie Meyer, Marie Wiklund, Pär Wingren, Petru Liuba, Erik Hedström

Abstract read
In one paragraph

Article in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. How to perform and evaluate a myocardial perfusion imaging by computed tomography.European heart journal. Imaging methods and practice · 2025
    Review
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fredrik StålhammarDiagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Marie-Louise AurumskjöldMedical Radiation Physics, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.ORCID 0009-0000-7044-2419
Sofie MeyerDiagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Marie WiklundDiagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Pär WingrenDiagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Petru LiubaPaediatric Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.ORCID 0000-0002-9680-4972
Erik HedströmDiagnostic Radiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. erik.hedstrom@med.lu.se.ORCID 0000-0003-0041-9357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhoton-counting computed tomography (PCCT) is a new clinical method that may show better diagnostic quality at lower radiation doses than conventional CT.

objectiveTo investigate the diagnostic quality and radiation dose of paediatric cardiovascular PCCT for diagnosis of congenital heart defects at 70 kV and 90 kV. MATERIALS AND

methodsThis retrospective assessment included clinical non-gated paediatric PCCT examinations for assessment of congenital heart defects. Radiation doses were recorded, and overall and specific diagnostic quality (1-4) were scored by four paediatric radiologists. Agreement, differences, and trends were assessed by percent rater agreement, intraclass correlation, Mann-Whitney tests, and Jonckheere-Terpstra tests.

resultsSeventy children with congenital heart defects were examined at 70 kV (n = 35; age 2 days-16 years; 63% boys) or 90 kV (n = 35; age 2 days-17 years; 51% boys). All observers gave a median score of 4 (high diagnostic quality) for both 70 kV and 90 kV, with no difference in median values between tube voltages (all P > 0.06). Agreement for overall scores was 66-94% for 70 kV and 60-77% for 90 kV. Agreement for specific scores was 80-97% for 70 kV and 83-89% for 90 kV. Size-dependent dose estimate was 0.68 mGy (0.25-2.02 mGy) for 70 kV and 1.10 mGy (0.58-2.71 mGy; P < 0.001) for 90 kV. Effective dose was 0.30 mSv (0.15-0.82 mSv) for 70 kV and 0.39 mSv (0.22-1.51 mSv; P = 0.01) for 90 kV.

conclusionPaediatric cardiovascular PCCT yields images for congenital heart defects of high diagnostic quality with low radiation dose at both 70 kV and 90 kV.

Indexed as

Heart Defects, CongenitalRadiation DosageTomography, X-Ray ComputedAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMalePhotonsReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityDiagnosisHeart defects, congenitalPaediatricsPhoton-counting computed tomographyRadiation dosage

Identifiers

PMID38700554
PMCPMC11182870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.