Evidence map›Paper›PMID 38700539›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Long-term follow-up results of facial nerve schwannoma with good facial nerve function: a multicenter study.

Young Sang Cho, Jong Dae Lee, Yang-Sun Cho, Jun Ho Lee, Hee Won Seo, Jang Wook Gwak, In Seok Moon, Jin Woong Choi, Gyu Cheol Han, Ja-Won Koo and 1 more

Abstract readMulticenter Study
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Young Sang Cho *Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-4040-7206
Jong Dae Lee *Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-2866-9841
Yang-Sun ChoDepartment of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-9180-2903
Jun Ho LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-5519-3263
Hee Won SeoDepartment of Otorhinolaryngology-Head and Neck Surgery, Hanyang University Guri Hospital, Hanyang University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0006-7795-1498
Jang Wook GwakDepartment of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-5200-0609
In Seok MoonDepartment of Otorhinolaryngology-Head and Neck Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-3951-5074
Jin Woong ChoiDepartment of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0003-3101-6841
Gyu Cheol HanDepartment of Otorhinolaryngology-Head and Neck Surgery, Gil Hospital, Gachon University, Incheon, Republic of Korea.ORCID http://orcid.org/0000-0002-0112-8183
Ja-Won KooDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam-Si, Republic of Korea. jwkoo99@snu.ac.kr.ORCID http://orcid.org/0000-0002-5538-2785
Jong Woo ChungDepartment of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. jwchung@amc.seoul.kr.ORCID http://orcid.org/0000-0003-0765-9134

Funding

Korea Health Industry Development Institute HR21C0885Ministry of Education, Science and Technology NRF- 2022M3E5E908221711
6 · The paper itself

Abstract

purposeFacial nerve schwannomas (FNSs) are rare intracranial tumors, and the optimal management of these tumors remains unclear. We investigated the long-term follow-up results of FNS with good facial nerve function.

methodsAt nine medical centers in the Korean Facial Nerve Study Group, 43 patients undergoing observation periods longer than 12 months for FNS with good facial nerve function (House-Brackmann grade ≤ II) were enrolled, and clinical and radiographic data were obtained for these cases.

resultsThe mean follow-up period was 63 months. In the majority of cases, tumors involved multiple segments (81.4%) and only eight cases were confined to a single site. There were no cases where the tumor was confined to the extratemporal region. Tumor size increased slightly, with an average estimated change of 0.48 mm/year. Twenty (46.5%) of 43 patients showed no change in tumor size. Seven patients (16.3%) showed worsening House-Brackmann (H-B) grade, of which two patients deteriorated from H-B grade I to II, four worsened to grade III, and one deteriorated to grade IV. The remaining 36 patients (83.7%) showed no change in facial nerve function. There was no difference in H-B grade according to tumor size at the time of diagnosis or change in tumor size.

conclusionWe conducted a large-scale observational study of FNS with good facial nerve function. Our study showed that many patients maintained facial nerve function during long-term follow-up. Conservative management with regular examination and imaging can be an appropriate option for managing FNS with good facial nerve function.

Indexed as

Cranial Nerve NeoplasmsNeurilemmomaAdolescentAdultAgedFacial NerveFacial Nerve DiseasesFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesYoung AdultFacial nerve functionFacial nerve schwannomaFacial palsyHouse–Brackmann gradeMulticenter study

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.