Evidence map›Paper›PMID 38700537›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Study on the correlation of C-reactive protein/albumin ratio with sudden sensorineural hearing loss complicated by hypertension: a prospective study.

Xu Zhang, Aijuan Cao, Qiuling Dang, Wentao Zhang, Yao Zhang, Maohua Wang, Bing Guan, Enze Wu, Yunlong Hu

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xu Zhang *Department of Otolaryngology, Head and Neck Surgery, Dalian Medical University, Dalian, 116000, China.
Aijuan Cao *Department of Otolaryngology, Dongtai Municipal People's Hospital of Nantong University, No. 2 Kangfu West Road, Yancheng, 224200, Jiangsu, China.
Qiuling DangDepartment of Digestive Medicine, Nanbu People's Hospital, Nanchong, 637300, Sichuan, China.
Wentao ZhangDepartment of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230031, China.
Yao ZhangDepartment of Otolaryngology, Head and Neck Surgery, Dalian Medical University, Dalian, 116000, China.
Maohua WangDepartment of Otolaryngology, Head and Neck Surgery, The First People's Hospital of Foshan, Hearing and Balance Medical Engineering Technology Center of Guangdong, Foshan, 528000, China.
Bing GuanDepartment of Otolaryngology, Head and Neck Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225001, China.
Enze WuDepartment of Talent Work, Nanjing University of Posts and Telecommunications, Nanjing, 210000, China. wuenze@njupt.edu.cn.
Yunlong HuDepartment of Otolaryngology Head and Neck Surgery, Anhui No.2 Provincial People's Hospital, Hefei, 230041, China. yunhuent@163.com.

Funding

Foundation Research Project of Jiangsu Province BK20201220
6 · The paper itself

Abstract

backgroundUnderstanding the pathophysiology of sudden sensorineural hearing loss (SSNHL) and identifying its clinical symptoms and associated risk factors are crucial for doctors in order to create effective prevention and therapeutic methods for this prevalent otolaryngologic emergency.

methodsThis study focuses on investigating the correlation between the C-reactive protein/albumin ratio (CAR) and SSNHL complicated by hypertension. In this study, 120 patients diagnosed with SSNHL were divided into groups with and without hypertension, and propensity score matching was used to compare and analyze the severity, type, prognosis, and CAR levels in SSNHL.

resultsThe results showed that the SSNHL group with hypertension had significantly higher CAR levels, age, hearing curve abnormalities, and more severe hearing loss compared to the control group with isolated SSNHL. These differences were statistically significant (p < 0.001). Among different subtypes of SSNHL, CAR levels increased progressively with the advancement of the condition, and these differences were also statistically significant (p < 0.001).

conclusionIn summary, in patients with SSNHL, those with hypertension had higher CAR levels than those without a history of hypertension, and they experienced more severe hearing loss. Moreover, there was a clear correlation between CAR levels and the extent of SSNHL, indicating that greater CAR levels in patients with SSNHL are connected to more severe hearing loss in various hearing patterns and perhaps indicative of a poorer prognosis.

Indexed as

C-Reactive ProteinHearing Loss, SensorineuralHearing Loss, SuddenHypertensionAdultAgedBiomarkersFemaleHumansMaleMiddle AgedPrognosisPropensity ScoreProspective StudiesRisk FactorsSerum AlbuminBiomarkersC-Reactive ProteinSerum AlbuminCARPropensity score matchingSSNHLSSNHL complicated by hypertension

Identifiers

PMID38700537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.