Evidence map›Paper›PMID 38700366›Full record

ArticleBalkan medical journal2024

Radiological Features for Predicting the Status of CD8-Positive Lymphocytes in HER2 Positive Breast Cancer.

Yuhong Fan, Xiaoguang Li, Peng Zhong, Hong Guo, Dong Han, Wuguo Tian, Jingqin Fang

Abstract read
In one paragraph

Article in Balkan medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuhong FanDepartment of Ultrasound Diagnosis, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-5232-4478
Xiaoguang LiDepartment of Radiology, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-7410-4134
Peng ZhongDepartment of Pathology, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0002-6966-8549
Hong GuoDepartment of Radiology, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0002-9565-890X
Dong HanDepartment of Ultrasound Diagnosis, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0002-9495-3835
Wuguo TianDepartment of Breast and Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-6414-6808
Jingqin FangDepartment of Ultrasound Diagnosis, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-5521-1778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The level of tumor-infiltrating lymphocytes (TILs) in human epidermal growth factor receptor type 2 (HER2)-positive breast cancer (BC) is positively correlated with pathological complete response. Aims: To investigate the relationship between ultrasound (US) and magnetic resonance imaging (MRI) features and the level of CD8-positive TILs (CD8 Study Design: Retrospective cohort study. Methods: This retrospective study included 155 consecutive women with HER2-positive BC. Patients were divided into two groups: CD8 Results: Univariate analysis of US features showed significant differences in shape, orientation, and posterior echo between the two groups; however, there were no significant differences in margins, internal echo, and microcalcification. Multifactorial analysis revealed that shape, orientation, and posterior echo were independent risk factors, with odds ratios of 11.62, 2.70, and 0.16, respectively. In terms of MRI features, ADC was an independent predictor of CD8 Conclusion: US features (shape, orientation, and posterior echo) and ADC value may be a valuable tool for estimating CD8

Indexed as

Breast NeoplasmsCD8-Positive T-LymphocytesErb-b2 Receptor Tyrosine KinasesMagnetic Resonance ImagingAdultAgedCohort StudiesFemaleHumansLymphocytes, Tumor-InfiltratingMiddle AgedRetrospective StudiesUltrasonographyERBB2 protein, humanErb-b2 Receptor Tyrosine Kinases

Identifiers

PMID38700366
PMCPMC11077930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.