Evidence map›Paper›PMID 38699955›Full record

ArticleJournal of pediatric psychology2025

Using the consolidated framework for implementation research to identify challenges and opportunities for implementing a reproductive health education program into sickle cell disease care.

Zachary A Colton, Sophia M Liles, Megan M Griffith, Charis J Stanek, Joseph Walden, Allison King, Toyetta Barnard-Kirk, Susan Creary, Leena Nahata

Abstract read
In one paragraph

Article in Journal of pediatric psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zachary A ColtonCenter for Biobehavioral Health, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0002-1065-6092
Sophia M LilesCenter for Biobehavioral Health, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0003-2883-9695
Megan M GriffithCenter for Biobehavioral Health, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0009-0006-8868-126X
Charis J StanekCenter for Biobehavioral Health, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0002-9937-0743
Joseph WaldenCenter for Child Health Equity and Outcomes Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0002-4111-1845
Allison KingDepartment of Pediatrics, Washington University in St Louis, St Louis, MO, United States.ORCID 0000-0002-1951-6176
Toyetta Barnard-KirkDepartment of Social Work at Nationwide Children's Hospital, Columbus, OH, United States.
Susan CrearyCenter for Child Health Equity and Outcomes Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0002-4730-8139
Leena NahataCenter for Biobehavioral Health, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.ORCID 0000-0003-3899-2642

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
Optimizing fertility preservation and decision quality in male AYA with cancer: A family-centered interventionK08CA237338 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI NAHATA, LEENA · 2019 to 2023
$1.0M
National Institutes of Health/National Cancer Institute K08CA237338NCATS NIH HHS UL1 TR002733NCI NIH HHS K08 CA237338NCI NIH HHS K08CA237338NIH HHSThe Ohio State University Center for Clinical and Translational Science UL1TR002733
6 · The paper itself

Abstract

backgroundAs survival rates for individuals with sickle cell disease (SCD) increase, calls have been made to improve their reproductive healthcare and outcomes. The research team created a web-based program entitled Fertility edUcaTion to Understand ReproductivE health in Sickle cell disease (FUTURES). The study aim was to use the Consolidated Framework for Implementation Research (CFIR) during pre-implementation to identify challenges and opportunities from the individual to systems level of implementation to ultimately optimize the integration of FUTURES into clinical practice.

methodsSemi-structured interviews were conducted with clinicians, research team members, and adolescent and young adult (AYA) males with SCD and their caregivers who participated in pilot testing. Interviews (N = 31) were coded inductively and then mapped onto CFIR domains (i.e., outer setting, inner setting, characteristics of individuals, and intervention characteristics).

resultsResearch team interviews indicated the lack of universal guidelines for reproductive care in this population and gaps in reproductive health knowledge as key reasons for developing FUTURES, also highlighting the importance of collaboration with community members during development. Clinicians reported intraorganizational communication as essential to implementing FUTURES and discussed challenges in addressing reproductive health due to competing priorities. Clinicians, AYAs, and caregivers reported positive views of FUTURES regarding length, engagement, accessibility, and content. Suggestions for the best setting and timing for implementation varied.

conclusionsUsing CFIR during the pre-implementation phase highlighted challenges and opportunities regarding integrating this program into SCD care. These findings will inform adaptation and further testing of FUTURES to ensure effective implementation of this novel education program.

Indexed as

Anemia, Sickle CellHealth EducationHealth Knowledge, Attitudes, PracticeReproductive HealthAdolescentAdultFemaleHumansImplementation ScienceMaleQualitative ResearchYoung Adultadolescentsdissemination & implementation sciencehematologyparentssexual or reproductive healthsickle cell disease

Identifiers

PMID38699955
PMCPMC11753835

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.