Evidence map›Paper›PMID 38699852›Full record

ReviewThe British journal of psychiatry : the journal of mental science2024

LGI1-antibody encephalitis: how to approach this highly treatable dementia mimic in memory and mental health services.

Sophie N M Binks, Adam Al-Diwani, Adam E Handel, Tomasz Bajorek, Sanjay Manohar, Masud Husain, Sarosh R Irani, Ivan Koychev

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The British journal of psychiatry : the journal of mental science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sophie N M BinksOxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.ORCID 0000-0003-0991-5998
Adam Al-DiwaniUniversity Department of Psychiatry, University of Oxford, UK.ORCID 0000-0001-6596-7579
Adam E HandelOxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.
Tomasz BajorekDepartment of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.
Sanjay ManoharDepartment of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.
Masud HusainDepartment of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.
Sarosh R IraniOxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.
Ivan KoychevUniversity Department of Psychiatry, University of Oxford, UK; and Department of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.

Funding

Academy of Medical Sciences Starter Grant for Clinical Lecturers SGL027\1016Medical Research Council Dementias Platform UKMedical Research Council MC_PC_17205Medical Research Council MR/P00878/XMedical Research Council MR/P00878X/1Medical Research Council MR/V007173/1NIHR Oxford Biomedical Research CentreUCB PharmaWellcome Trust 104079/Z/14/ZWellcome Trust 206330Wellcome Trust 206330/Z/17/Z
6 · The paper itself

Abstract

Leucine-rich glioma-inactivated 1-antibody-encephalitis is a treatable and potentially reversible cause of cognitive and psychiatric presentations, and may mimic cognitive decline, rapidly progressive dementia and complex psychosis in older patients. This aetiology is of immediate relevance given the alternative treatment pathway required, compared with other conditions presenting with cognitive deficits.

Indexed as

AutoantibodiesDementiaAgedDiagnosis, DifferentialEncephalitisFemaleHumansIntracellular Signaling Peptides and ProteinsMaleMental Health ServicesAutoantibodiesIntracellular Signaling Peptides and ProteinsLGI1 protein, humanDementialeucine-rich glioma-inactivated 1neuroimmunologyolder adultspsychosis

Identifiers

PMID38699852
PMCPMC7615977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.