Evidence map›Paper›PMID 38699435›Full record

ReviewFrontiers in bioengineering and biotechnology2024

Unlocking the potential of exosomes: a breakthrough in the theranosis of degenerative orthopaedic diseases.

Yaohang Yue, Wei Dai, Yihao Wei, Siyang Cao, Shuai Liao, Aikang Li, Peng Liu, Jianjing Lin, Hui Zeng

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Exosomes in cartilage microenvironment regulation and cartilage repair.Frontiers in cell and developmental biology · 2025
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaohang Yue *School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Wei Dai *School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Yihao Wei *Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Siyang CaoPeking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Shuai LiaoPeking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Aikang LiPeking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Peng Liu *Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Jianjing Lin *Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Hui Zeng *School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative orthopaedic diseases pose a notable worldwide public health issue attributable to the global aging population. Conventional medical approaches, encompassing physical therapy, pharmaceutical interventions, and surgical methods, face obstacles in halting or reversing the degenerative process. In recent times, exosome-based therapy has gained widespread acceptance and popularity as an effective treatment for degenerative orthopaedic diseases. This therapeutic approach holds the potential for "cell-free" tissue regeneration. Exosomes, membranous vesicles resulting from the fusion of intracellular multivesicles with the cell membrane, are released into the extracellular matrix. Addressing challenges such as the rapid elimination of natural exosomes

Indexed as

exosomesintervertebral disc degenerationosteoarthritisosteoporosistreatment

Identifiers

PMID38699435
PMCPMC11064847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.