Evidence map›Paper›PMID 38699390›Full record

ArticleFrontiers in endocrinology2024

Positive association between blood ethylene oxide levels and metabolic syndrome: NHANES 2013-2020.

Chunqi Zhou, Senlin Wang, Lingling Ju, Ruimin Zhang, Yunning Yang, Yanjun Liu

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  8. Association of ethylene oxide exposure and obstructive sleep apnea.Environmental health and preventive medicine · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Chunqi Zhou *College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Senlin Wang *Department of General Surgery, Affiliated Hospital of Southwest Jiaotong University, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Lingling Ju *College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Ruimin ZhangCollege of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Yunning YangDepartment of General Surgery, Affiliated Hospital of Southwest Jiaotong University, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
Yanjun LiuCollege of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The exposure of Ethylene oxide (EO) is linked to systemic inflammatory response and various cardiovascular risk factors. Hemoglobin's binding to ethylene oxide (HbEO) was used to measure serum EO level. This research aims to explore the association between metabolic syndrome (MetS) and HbEO, and between HbEO and components of metabolic syndrome. Method: This research included 1842 participants from 2013 to 2020 in National Health and Nutrition Examination Survey (NHANES) database. Weighted logistic regression models were used to analyze the relationship between HbEO and metabolic syndrome risk, using odds ratio (OR) and 95% confidence interval (CI). The restricted cubic spline plot explores whether there is a dose-response relationship between HbEO and MetS risk. Subgroup analysis was performed to analyze study heterogeneity. Results: Significant differences were found in gender, educational level, marital status, diabetes status and hypertension among different groups ( Conclusion: This study indicates a linear correlation between MetS and HbEO, with MetS risk escalating as HbEO levels increase. The prevalence of MetS varies depending on BMI, age and gender, and these factors can also influence MetS prevalence when exposed to EO.

Indexed as

Ethylene OxideMetabolic SyndromeNutrition SurveysAdultAgedCross-Sectional StudiesFemaleHemoglobinsHumansMaleMiddle AgedRisk FactorsEthylene OxideHemoglobinsepidemiologyethylene oxideinflammationmetabolic syndromeNHANES

Identifiers

PMID38699390
PMCPMC11063307

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.