Evidence map›Paper›PMID 38699362›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Accurate prediction of neurologic changes in critically ill infants using pose AI.

Alec Gleason, Florian Richter, Nathalia Beller, Naveen Arivazhagan, Rui Feng, Emma Holmes, Benjamin S Glicksberg, Sarah U Morton, Maite La Vega-Talbott, Madeline Fields and 3 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Alec GleasonAlbert Einstein College of Medicine, New York, NY.
Florian RichterFloDri Inc, San Francisco, CA.
Nathalia BellerDepartment of Genetics, Icahn School of Medicine at Mount Sinai, New York, NY.
Naveen ArivazhaganDivision of Data Driven and Digital Medicine (D3M), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Rui FengDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY.
Emma HolmesThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Benjamin S GlicksbergDepartment of Genetics, Icahn School of Medicine at Mount Sinai, New York, NY.
Sarah U MortonDepartment of Pediatrics, Harvard Medical School, Boston, MA.
Maite La Vega-TalbottDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY.
Madeline FieldsDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY.
Katherine GuttmannDivision of Newborn Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Girish N NadkarniDivision of Data Driven and Digital Medicine (D3M), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Felix RichterDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0003-3429-9621

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
NCATS NIH HHS UL1 TR004419NIH HHS S10 OD026880NIH HHS S10 OD030463
6 · The paper itself

Abstract

Infant alertness and neurologic changes can reflect life-threatening pathology but are assessed by exam, which can be intermittent and subjective. Reliable, continuous methods are needed. We hypothesized that our computer vision method to track movement, pose AI, could predict neurologic changes in the neonatal intensive care unit (NICU). We collected 4,705 hours of video linked to electroencephalograms (EEG) from 115 infants. We trained a deep learning pose algorithm that accurately predicted anatomic landmarks in three evaluation sets (ROC-AUCs 0.83-0.94), showing feasibility of applying pose AI in an ICU. We then trained classifiers on landmarks from pose AI and observed high performance for sedation (ROC-AUCs 0.87-0.91) and cerebral dysfunction (ROC-AUCs 0.76-0.91), demonstrating that an EEG diagnosis can be predicted from video data alone. Taken together, deep learning with pose AI may offer a scalable, minimally invasive method for neuro-telemetry in the NICU.

Identifiers

PMID38699362
PMCPMC11064996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.