Evidence map›Paper›PMID 38699219›Full record

ArticleJournal of immunology research2024

Clinical Characteristics of EGPA Patients in Comparison to GPA Subgroup with Increased Blood Eosinophilia from POLVAS Registry.

Anna Drynda, Agnieszka Padjas, Krzysztof Wójcik, Radosław Dziedzic, Grzegorz Biedroń, Katarzyna Wawrzycka-Adamczyk, Anna Włudarczyk, Joanna Wilańska, Jacek Musiał, Zbigniew Zdrojewski and 28 more

Abstract readComparative Study
In one paragraph

Article in Journal of immunology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Anna DryndaStudents' Scientific Group of Immune Diseases and Hypercoagulation, Jagiellonian University Medical College, Cracow, Poland.ORCID https://orcid.org/0009-0009-5556-2637
Agnieszka Padjas2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Krzysztof Wójcik2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Radosław DziedzicDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Cracow, Poland.ORCID https://orcid.org/0000-0003-0321-3557
Grzegorz Biedroń2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Katarzyna Wawrzycka-Adamczyk2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Anna Włudarczyk2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Joanna Wilańska2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Jacek Musiał2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.
Zbigniew ZdrojewskiDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Gdansk, Poland.
Zenobia CzuszyńskaDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Gdansk, Poland.
Anna MasiakDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Gdansk, Poland.
Maria MajdanDepartment of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.
Radosław JeleniewiczDepartment of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.
Hanna Augustyniak-BartosikDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Katarzyna JakuszkoDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Magdalena KrajewskaDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Alicja Dębska-ŚlizieńDepartment of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, Gdansk, Poland.
Hanna StoroniakDepartment of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, Gdansk, Poland.
Barbara Bułło-PionteckaDepartment of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, Gdansk, Poland.
Witold TłustochowiczDepartment of Internal Medicine and Rheumatology, Military Medical Institute, Warsaw, Poland.
Joanna Kur-ZalewskaDepartment of Internal Medicine and Rheumatology, Military Medical Institute, Warsaw, Poland.
Małgorzata WisłowskaDepartment of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Piotr GłuszkoDepartment of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Marta MadejDepartment of Rheumatology and Internal Medicine, Wroclaw Medical University, Wroclaw, Poland.
Ewa JassemDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Iwona Damps-KonstańskaDepartment of Allergology, Medical University of Gdansk, Gdansk, Poland.
Eugeniusz KucharzDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Marek BrzoskoDepartment of Rheumatology, Internal Medicine, Diabetology, Geriatrics and Clinical Immunology with the Gastroenterology Unit, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Marcin MilchertDepartment of Rheumatology, Internal Medicine, Diabetology, Geriatrics and Clinical Immunology with the Gastroenterology Unit, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Anna Hawrot-KaweckaDepartment of Internal Medicine and Metabolic Diseases, Medical University of Silesia, Katowice, Poland.
Joanna Miłkowska-DymanowskaDepartment of Pneumology, Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland.
Paweł GórskiDepartment of Pneumology, Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland.
Anna Lewandowska-PolakDepartment of Rheumatology, Medical University of Lodz, Lodz, Poland.
Joanna MakowskaDepartment of Rheumatology, Medical University of Lodz, Lodz, Poland.
Joanna ZalewskaDepartment of Rheumatology and Connective Tissue Diseases, Ludwik Rydygier Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Lech ZarębaInstitute of Computer Science, College of Natural Sciences, University of Rzeszow, Rzeszow, Poland.
Stanisława Bazan-Socha2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.ORCID https://orcid.org/0000-0001-9634-0963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To characterize the eosinophilic granulomatosis with polyangiitis (EGPA) population from the POLVAS registry depending on ANCA status and diagnosis onset, including their comparison with the granulomatosis with polyangiitis (GPA) subset with elevated blood eosinophilia (min. 400/ Methods: A retrospective analysis of the POLVAS registry. Results: The EGPA group comprised 111 patients. The ANCA-positive subset ( Conclusion: Cardiovascular symptoms were more prevalent in the ANCA-negative subset than in the MPO-ANCA-positive one. Since EGPA and GPE HE share similarities in clinics, diagnostic misleading may result in an inappropriate therapeutic approach. Further studies are needed to optimize their differentiation and tailored therapy, including biologics.

Indexed as

Antibodies, Antineutrophil CytoplasmicEosinophiliaRegistriesAdultAgedChurg-Strauss SyndromeEosinophilsFemaleGranulomatosis with PolyangiitisHumansMaleMiddle AgedPeroxidaseRetrospective StudiesAntibodies, Antineutrophil CytoplasmicPeroxidase

Identifiers

PMID38699219
PMCPMC11065486

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.