Evidence map›Paper›PMID 38699170›Full record

ArticleArXiv2025

Virtual Lung Screening Trial (VLST): An

Fakrul Islam Tushar, Liesbeth Vancoillie, Cindy McCabe, Amareswararao Kavuri, Lavsen Dahal, Brian Harrawood, Milo Fryling, Mojtaba Zarei, Saman Sotoudeh-Paima, Fong Chi Ho and 9 more

Abstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Fakrul Islam TusharCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Liesbeth VancoillieCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Cindy McCabeCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Amareswararao KavuriCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Lavsen DahalCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Brian HarrawoodCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Milo FrylingCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Mojtaba ZareiCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Saman Sotoudeh-PaimaCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Fong Chi HoCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Dhrubajyoti GhoshDept. of Biostatistics and Bioinformatics, Duke University School of Medicine.
Michael R HarowiczCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Tina D TailorCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Sheng LuoDept. of Biostatistics and Bioinformatics, Duke University School of Medicine.
W Paul SegarsCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Ehsan AbadiCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Kyle J LafataCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Joseph Y LoCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.
Ehsan SameiCenter for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Dept. of Radiology, Duke University School of Medicine.

Funding

TR&D Project 3: Virtual ReadersP41EB028744 · NIBIB · DUKE UNIVERSITY · PI Ehsan Samei · 2021 to 2026
$7.8M
Simulation Tools for Dynamic CTR01EB001838 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2005 to 2023
$6.9M
Computer-Aided Triage of Body CT Scans with Deep LearningR01CA261457 · NCI · DUKE UNIVERSITY · PI LO, JOSEPH Y, RUBIN, GEOFFREY D · 2023 to 2025
$2.3M
Accuracy and Precision in CT Quantification of COPD Through Virtual Imaging TrialsR01HL155293 · NHLBI · DUKE UNIVERSITY · PI ABADI, EHSAN · 2021 to 2025
$2.2M
NCI NIH HHS R01 CA261457NHLBI NIH HHS R01 HL155293NIBIB NIH HHS P41 EB028744NIBIB NIH HHS R01 EB001838
6 · The paper itself

Abstract

Clinical imaging trials play a crucial role in advancing medical innovation but are often costly, inefficient, and ethically constrained. Virtual Imaging Trials (VITs) present a solution by simulating clinical trial components in a controlled, risk-free environment. The Virtual Lung Screening Trial (VLST), an

Indexed as

chest radiography (CXR)Computed tomography (CT)Computer-aided diagnosisHuman Digital TwinsNational Lung Screening Trials (NLST)Neural NetworksVirtual Lung Screening Trial (VLST)

Identifiers

PMID38699170
PMCPMC11065052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.