Evidence map›Paper›PMID 38699066›Full record

ArticleDrugs in context2024

Cost-effectiveness of albumin in the treatment of decompensated cirrhosis in resource-limited healthcare settings.

Irsan Hasan, Ignatia Sinta Murti, Putut Bayupurnama, Kemal Fariz Kalista, Christina Hill-Zabala, Dennis Kananda, Elisabet Viayna

Abstract read
In one paragraph

Article in Drugs in context, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Low-Dose vs. Standard Care Iv Human Albumin During Large-Volume Paracentesis in Patients With Liver Cirrhosis: A Systematic Review.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Article
  3. Article
  4. Efficacy of albumin use in decompensated cirrhosis and real-world adoption in Australia.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irsan HasanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia.ORCID https://orcid.org/0000-0001-6702-2659
Ignatia Sinta MurtiDepartment of Internal Medicine, Abdul Wahab Sjahranie General Hospital Samarinda, East Kalimantan, Indonesia.ORCID https://orcid.org/0000-0002-0117-2088
Putut BayupurnamaGastroenterology & Hepatology Division, Department of Internal Medicine, Dr. Sardjito General Hospital/Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0003-4564-8911
Kemal Fariz KalistaHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-4001-2378
Christina Hill-ZabalaGrifols Asia Pacific Pte Ltd, Singapore.ORCID https://orcid.org/0009-0004-9808-1116
Dennis KanandaIQVIA, Jakarta, Indonesia.ORCID https://orcid.org/0009-0004-1358-4719
Elisabet ViaynaGrifols SA, Sant Cugat del Vallès, Spain.ORCID https://orcid.org/0000-0003-3253-0148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Human albumin (HA) is an effective adjuvant treatment for patients with cirrhosis developing spontaneous bacterial peritonitis (SBP), hepatorenal syndrome (HRS) and ascites requiring large-volume paracentesis (LVP). However, cost remains a barrier to use, particularly in resource-limited settings. This study aims to assess the cost-effectiveness of HA in patients with cirrhosis with SBP, HRS or ascites requiring LVP in the Indonesian healthcare system as a representative of a resource-limited setting. Methods: Three decision-tree models were developed to assess the cost-effectiveness of (1) antibiotics and HA Results: The ICER for antibiotics and HA ( Conclusion: Adjunctive HA may be a cost-effective treatment for SBP, HRS and LVP in resource-limited settings.

Indexed as

cost-effectivenesshuman albuminIndonesialiver cirrhosisliver diseasesresource-limited settings

Identifiers

PMID38699066
PMCPMC11065133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.