Evidence map›Paper›PMID 38698944›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2024

Epidemiology of carbapenem-resistant organisms in Alameda County, California, 2019-2021.

Rachel Marusinec, Munira Shemsu, Tyler Lloyd, Brendan M Kober, Dustin T Heaton, Jade A Herrera, Misha Gregory, Vici Varghese, Joelle Nadle, Kavita K Trivedi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel MarusinecAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.ORCID https://orcid.org/0000-0001-8880-4799
Munira ShemsuAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.
Tyler LloydAlameda County Health, Public Health Department, Public Health Laboratory, Oakland, CA, USA.ORCID https://orcid.org/0000-0002-4581-4871
Brendan M KoberAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.
Dustin T HeatonAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.
Jade A HerreraAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.
Misha GregoryAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.
Vici VargheseAlameda County Health, Public Health Department, Public Health Laboratory, Oakland, CA, USA.
Joelle NadleCalifornia Emerging Infections Program, Oakland, CA, USA.
Kavita K TrivediAlameda County Health, Public Health Department, Division of Communicable Disease Control and Prevention, San Leandro, CA, USA.ORCID https://orcid.org/0000-0001-7538-684X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Carbapenem-resistant organisms (CROs) are an urgent health threat. Since 2017, Alameda County Health Public Health Department (ACPHD) mandates reporting of carbapenem-resistant Enterobacterales (CRE) and encourages voluntary reporting of non-CRE CROs including carbapenem-resistant Methods: Healthcare facilities in Alameda County reported CRO cases and submitted isolates to ACPHD to characterize carbapenemase genes; deaths were identified via the California Electronic Death Registration System. CRO cases with isolates resistant to one or more carbapenems were analyzed from surveillance data from July 2019 to June 2021. Results: Four hundred and forty-two cases of CROs were reported to Alameda County from 408 patients. The county case rate for CROs was 29 cases per 100,000 population, and cases significantly increased over the 2-year period. CRPA was most commonly reported (157 cases, 36%), and cases of CRAB increased 1.83-fold. One-hundred eighty-six (42%) cases were identified among residents of long-term care facilities; 152 (37%) patients had died by January 2022. One hundred and seven (24%) cases produced carbapenemases. Conclusions: The high burden of CROs in Alameda County highlights the need for continued partnership on reporting, testing, and infection prevention to limit the spread of resistant organisms. A large proportion of cases were identified in vulnerable long-term care residents, and CRAB was an emerging CRO among this population. Screening for CROs and surveillance at the local level are important to understand epidemiology and implement public health interventions.

Identifiers

PMID38698944
PMCPMC11062789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.