Evidence map›Paper›PMID 38698860›Full record

ReviewFrontiers in immunology2024

Steroid receptor coactivators in Treg and Th17 cell biology and function.

Yosi Gilad, Ortal Shimon, Sang Jun Han, David M Lonard, Bert W O'Malley

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yosi GiladDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.
Ortal ShimonDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.
Sang Jun HanDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.
David M LonardDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.
Bert W O'MalleyDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.

Funding

REPRODUCTIVE HORMONES: BIOLOGICAL AND MOLECULAR ACTIONSR01HD008188 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI DAVID M LONARD, JOHN P LYDON · 1985 to 2026
$16.3M
SEX HORMONE RECEPTOR COMPONENTS AND THE CELL GENOMER01HD007857 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI DAVID M LONARD, JOHN P LYDON · 1985 to 2026
$14.6M
NICHD NIH HHS R01 HD007857NICHD NIH HHS R01 HD008188
6 · The paper itself

Abstract

Steroid receptor coactivators (SRCs) are master regulators of transcription that play key roles in human physiology and pathology. SRCs are particularly important for the regulation of the immune system with major roles in lymphocyte fate determination and function, macrophage activity, regulation of nuclear factor κB (NF-κB) transcriptional activity and other immune system biology. The three members of the p160 SRC family comprise a network of immune-regulatory proteins that can function independently or act in synergy with each other, and compensate for - or moderate - the activity of other SRCs. Recent evidence indicates that the SRCs are key participants in governing numerous aspects of CD4

Indexed as

Th17 CellsT-Lymphocytes, RegulatoryHumansNeoplasmsNuclear Receptor CoactivatorsNuclear Receptor Coactivatorscell therapynuclear coactivators (NCoAs)steroid receptor coactivators (SRCs)Th17 cellsTreg cells

Identifiers

PMID38698860
PMCPMC11063348

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.