SynthesisBMC geriatrics2024
Effect of vitamin D, calcium, or combined supplementation on fall prevention: a systematic review and updated network meta-analysis.
Synthesis in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exercise and nutritional interventions for sarcopenia-related fall prevention in older adults: An umbrella review.The journal of nutrition, health & aging · 2026Pooled it
- Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2026Pooled it
- A Pilot Randomized Trial of a Program to Prevent Falls Among Community-Dwelling Adults Living with Mental Illness Demonstrates Feasibility.Inquiry : a journal of medical care organization, provision and financingTrial
- From the Vitamin D Paradox to Precision Nutrition: Targeted Supplementation, Assay Pitfalls, and Clinical Decision-Making.Current nutrition reports · 2026Review
- Medication Therapy Management Guided by TIME Criteria in Nursing Home Residents: A Before-After Observational Study.Journal of clinical medicine · 2026Article
- Diagnostic Accuracy of Point-of-Care Tests to Diagnose Vitamin D Deficiency in Adults and Children: Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation.Journal of orthopaedic translation · 2026Review
- Fall Prevention Interventions and Fracture Risk in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.Clinics and practice · 2026Review
- Nutritional status is linked to muscle strength and perceived function in adults with muscular dystrophy: evidence for targeted nutritional interventions.The British journal of nutrition · 2025Article
- Vitamin D and the aging skin: insights into oxidative stress, inflammation, and barrier function.Immunity & ageing : I & A · 2025Review
- Efficacy of Vitamin D Supplementation on the Risk of Falls Among Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Vitamin D and physical activity as co-modifiers of muscle health and function - a narrative exploration.Annals of medicine and surgery (2012) · 2025Review
- Updating STEADI for Primary Care: Recommendations From the American Geriatrics Society Workgroup.Journal of the American Geriatrics Society · 2025Article
- Identification of Priority Nutrients in the US: Targeting Malnutrition to Address Diet-Related Disease Across the Lifespan.Nutrients · 2025Article
- Article
- Vitamin D and hip protectors in osteosarcopenia: a combined hip fracture preventing approach.Reviews in endocrine & metabolic disorders · 2025Review
- Osteosarcopenia in metabolic dysfunction-associated steatotic liver disease: from mechanisms to management.Frontiers in endocrinology · 2025Review
- Aging and IGF-I: relationships with vitamin D and body composition. A mediation analysis.Frontiers in nutrition · 2025Article
- Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system.Scientific reports · 2024Article
- Calcium, Vitamin D, and Aging in Humans.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between vitamin D supplementation and the risk of falls in older adults has been controversial. This systematic review and network meta-analysis aims to assess the efficacy of vitamin D, calcium, and combined supplementation in the prevention of falls.
methodsRandomized controlled trials (RCTs) on the efficacy of vitamin D in fall prevention were systematically searched in PubMed, Embase, Cochrane Library, and Web of Science from inception to May 9, 2023. The network meta-analysis was performed using a random effects model in R4.1.3 and Stata15.0. Heterogeneity was evaluated by the I
resultsA total of 35 RCTs involving 58,937 participants were included in this study, among which 11 RCTs (31.4%) applied calcium combined with vitamin D. There was low heterogeneity (I
conclusionVitamin D supplementation at 800-1000 IU/d is associated with a lower risk of falls among older adults. 800-1000IU/d of vitamin D has a benefit on prevention of falls in population received daily dose regimens and in population with vitamin D deficiency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.