ReviewNature reviews. Cardiology2024
Stress and cardiovascular disease: an update.
Review in Nature reviews. Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
121 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Chronic psychosocial stress: a role in breast cancer etiology?Frontiers in oncology · 2026Pooled it
- Performance of artificial intelligence models for monitoring psychological stress using noncontact physiological signals: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis.Molecular psychiatry · 2025Pooled it
- The relation between stress-related neural activity assessed by brainEuropean journal of nuclear medicine and molecular imaging · 2025Pooled it
- Examining the Impact of Acute Exercise and Arousal Reappraisal on Stressor-Evoked Psychological and Cardiovascular Responses.Psychophysiology · 2026Trial
- Early-onset atherosclerotic cardiovascular disease in young adults: Lifestyle, environmental, and psychosocial risk factors.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Psychological distress and incident cardiovascular disease independent of life's essential 8: a prospective cohort study.Annals of medicine · 2026Article
- Plasma proteomic signatures of childhood adversity.Protein & cell · 2026Article
- Watching the Game, Skipping the Hospital: World Cup Matches and Cardiovascular Hospitalizations.Cardiology research · 2026Article
- The Risk of Cardiovascular Diseases for Shift Workers in the Prospective Heinz Nixdorf Recall Study.American journal of industrial medicine · 2026Article
- Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026Review
- Article
- Psychometric Evidence for Chronic Stress Patient-Reported Outcome Measures in African American Adults: An Equity-Focused COSMIN Systematic Review.Journal of racial and ethnic health disparities · 2026Review
- Biopsychosocial phenogroups in an urban population with coronary artery disease and their associations with adverse cardiovascular events.European heart journal open · 2026Article
- The emerging potential of the psycho-cardiovascular interaction network in precision medicine.Precision clinical medicine · 2026Article
- Psycho-cardiovascular interaction network in cardiovascular health and disease: signaling pathways and molecular mechanisms.Precision clinical medicine · 2026Review
- Multidimensional perspectives on cancer therapy-induced cardiotoxicity: Characteristics, mechanisms, biomarkers, psychological stress effects, and treatment progress.Cancer pathogenesis and therapy · 2026Review
- Machine Learning Approaches to Identify Influential Factors of the Comorbid Psychiatric Symptoms and Hypertension Among Rural Adults in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Impacts of Paid Family Leave on Perinatal Health: A Nationwide Quasi-Experimental Study.Pediatrics · 2026Article
- Repetitive pressure overload: species disparities, mechanisms, and translational relevance.American journal of physiology. Heart and circulatory physiology · 2026Article
61 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Psychological stress is generally accepted to be associated with an increased risk of cardiovascular disease (CVD), but results have varied in terms of how stress is measured and the strength of the association. Additionally, the mechanisms and potential causal links have remained speculative despite decades of research. The physiological responses to stress are well characterized, but their contribution to the development and progression of CVD has received little attention in empirical studies. Evidence suggests that physiological responses to stress have a fundamental role in the risk of CVD and that haemodynamic, vascular and immune perturbations triggered by stress are especially implicated. Stress response physiology is regulated by the corticolimbic regions of the brain, which have outputs to the autonomic nervous system. Variation in these regulatory pathways might explain interindividual differences in vulnerability to stress. Dynamic perturbations in autonomic, immune and vascular functions are probably also implicated as CVD risk mechanisms of chronic, recurring and cumulative stressful exposures, but more data are needed from prospective studies and from assessments in real-life situations. Psychological assessment remains insufficiently recognized in clinical care and prevention. Although stress-reduction interventions might mitigate perceived stress levels and potentially reduce cardiovascular risk, more data from randomized trials are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.