Evidence map›Paper›PMID 38697946›Full record

ArticlePhysiological reports2024

Association between arterial health and cognition in adolescents: The PANIC study.

Petri Jalanko, Bert Bond, Jari A Laukkanen, Soren Brage, Ulf Ekelund, Tomi Laitinen, Sara Määttä, Mika Kähönen, Eero A Haapala, Timo A Lakka

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In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Petri JalankoFaculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0002-8758-7275
Bert BondChildren's Health and Exercise Research Centre, Sport and Health Science, College of Life and Environmental Sciences, University of Exeter, Exeter, UK.ORCID 0000-0003-3597-8562
Jari A LaukkanenDepartment of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.ORCID 0000-0002-3738-1586
Soren BrageMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.ORCID 0000-0002-1265-7355
Ulf EkelundDepartment of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0003-2115-9267
Tomi LaitinenDepartment of Clinical Physiology and Nuclear Imaging, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0003-3553-9957
Sara MäättäDepartment of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0001-5402-3417
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-4510-7341
Eero A HaapalaFaculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0001-5096-851X
Timo A LakkaDepartment of Clinical Physiology and Nuclear Imaging, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0002-9199-2871

Funding

Aarne Koskelo FoundationDiabetes Research Foundation in FinlandFinnish Cultural FoundationFinnish Foundation for Cardiovascular ResearchFinnish Innovation Fund SitraFoundation for Paediatric ResearchJuho Vainio FoundationMinistry of Education and Culture of FinlandMinistry of Social Affairs and Health of FinlandPaavo Nurmi FoundationPäivikki and Sakari Sohlberg FoundationResearch Committee of the Kuopio University Hospital CatchmentSocial Insurance Institution of FinlandThe city of KuopioUrheiluopisto FoundationYrjö Jahnsson Foundation
6 · The paper itself

Abstract

We investigated the associations of the measures of arterial health with cognition in adolescents and whether physical activity (PA) or sedentary time (ST) confounds these associations. One hundred sixteen adolescents (71 boys) aged 15.9 ± 0.4 participated in the study. PA and ST were assessed using a combined accelerometer/heart rate monitor. Overall cognition was computed from the results of psychomotor function, attention, working memory, and paired-associate learning tests. Pulse wave velocity was measured by impedance cardiography, carotid intima-media thickness, and carotid artery distensibility by carotid ultrasonography. Systolic and diastolic blood pressure (SBP and DBP) were measured using an aneroid sphygmomanometer. SBP was inversely associated with overall cognition (standardized regression coefficient [β] = -0.216, 95% confidence interval (CI) -0.406 to -0.027, p = 0.025). Pulse wave velocity (β = -0.199, 95% CI -0.382 to -0.017, p = 0.033) was inversely associated with working memory task accuracy. SBP was directly associated with reaction time in the attention (β = 0.256, 95% CI 0.069 to 0.443, p = 0.008) and errors in the paired-associate learning tasks (β = 0.308, 95% CI 0.126 to 0.489, p = 0.001). Blood pressure was inversely associated with overall cognition. PA or ST did not confound the associations. Results suggest that preventing high blood pressure is important for promoting cognition in adolescents.

Indexed as

Blood PressureCognitionPulse Wave AnalysisAdolescentAttentionCarotid ArteriesCarotid Intima-Media ThicknessExerciseFemaleHeart RateHumansMaleMemory, Short-TermSedentary Behaviorarterial stiffnessblood pressurecarotid intima‐media thicknessphysical activitysedentary time

Identifiers

PMID38697946
PMCPMC11065692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.